Influência do consumo de suco de laranja no perfil sérico dos lípides, apolipoproteínas e homocisteína em homens normais e hiperlipidêmicos
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Data
2007-10-19
Autores
Bonifácio, Nancy Preising Aptekmann [UNESP]
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Universidade Estadual Paulista (Unesp)
Resumo
O objetivo deste estudo foi verificar a influência da ingestão de suco de laranja no perfil sérico de lípides, apolipoproteínas e homocisteína em indivíduos do sexo masculino, normais (NL) ou hiperlipidêmicos (HL). A amostra populacional foi constituída por 114 indivíduos, com idade entre 20 e 60 anos, trabalhadores de uma empresa de suco de laranja na cidade de Matão, SP. Foram realizadas avaliações antropométricas, bioquímicas e de consumo alimentar. A análise dos dados revelou grande proporção de indivíduos com hiperlipidemia (44%), obesidade (65%), hipertensão (18%) e hiper-homocisteinemia (56%). Os indivíduos HL apresentaram maiores valores de peso, IMC, circunferência abdominal, circunferência do braço, pressão arterial, colesterol total, colesterol de LDL (LDL-C) e apolipoproteína B (apo B), em comparação aos NL. Os indivíduos que consumiam suco de laranja (CS) dos grupos NL (343 ± 312 mL/dia durante 12 ± 3 meses) e HL (281 ± 205 mL/dia durante 13 meses) apresentaram menor concentração de LDL-C, respectivamente 15% e 13%, e menor teor de apo B, 11% e 9%, em comparação aos indivíduos que não tomavam suco (NS). Nos grupos NL– CS e HL– CS foi observada tendência de redução da razão LDL-C/HDL-C de 13% e 14%, respectivamente. A homocisteína sanguínea não foi diferente entre os grupos NL - CS e HL - CS. A ingestão dietética de energia, proteína e carboidratos dos indivíduos NL e HL estava de acordo com as cotas dietéticas recomendadas (DRI), mas o consumo de ácidos graxos saturados e colesterol estava aumentado, sendo estes parâmetros associados com o sobrepeso, obesidade e hiperlipidemia. Em conclusão, o consumo de suco de laranja foi associado a concentrações menores dos lípides séricos nos indivíduos NL e HL, podendo ser interpretado como um fator de proteção contra a doença cardíaca coronariana.
In this study, the influence of the consumption of orange juice on the blood lipid profile, apolipoproteins and homocystein in normal (NL) and hyperlipemic (HL) male subjects was analyzed. Sample population was composed of 114 workers, 20 to 60 years of age, from an Orange Juice Plant in Matao, SP, Brazil. Anthropometric, biochemical and dietary parameters were evaluated in these individuals. Statistical analysis has shown a considerable occurrence of hyperlipemia (44%), obesity (65%), hypertension (18%) and hyperhomocysteinemia (56%) among these subjects. HL subjects presented higher values for weight, BMI, abdominal and arm circumferences, blood pressure, total cholesterol, LDL cholesterol (LDL-C), and apolipoprotein B (apo B). In both NL (343 ± 312 mL/day, during 12 ± 3 months) and HL (281 ± 205 mL/day, during 13 months) groups, regular consumption of orange juice (CS) showed lower concentration of LDL, 15% and 13% respectively, as well as lower concentration of apo B, 11% and 9%, in comparison to subjects with no consumption of orange juice (NS). Furthermore, NL and HL – CS groups showed a tendency for low LDL-C/HDL-C ratio, respectively 13% and 14%. Homocysteine was not different between NL - CS and HL - CS groups. Dietary intake of energy, protein and carbohydrate was according to nutritional allowances (DRI) in the NL e HL subjects. In addition, large consumption of saturated fatty acid and dietary cholesterol were associated with overweight, obesity and hyperlipemia in this population. Finally, orange juice consumption was associated with lower levels of blood lipids in NL and HL subjects, and suggests a protector role against the coronary heart disease.
In this study, the influence of the consumption of orange juice on the blood lipid profile, apolipoproteins and homocystein in normal (NL) and hyperlipemic (HL) male subjects was analyzed. Sample population was composed of 114 workers, 20 to 60 years of age, from an Orange Juice Plant in Matao, SP, Brazil. Anthropometric, biochemical and dietary parameters were evaluated in these individuals. Statistical analysis has shown a considerable occurrence of hyperlipemia (44%), obesity (65%), hypertension (18%) and hyperhomocysteinemia (56%) among these subjects. HL subjects presented higher values for weight, BMI, abdominal and arm circumferences, blood pressure, total cholesterol, LDL cholesterol (LDL-C), and apolipoprotein B (apo B). In both NL (343 ± 312 mL/day, during 12 ± 3 months) and HL (281 ± 205 mL/day, during 13 months) groups, regular consumption of orange juice (CS) showed lower concentration of LDL, 15% and 13% respectively, as well as lower concentration of apo B, 11% and 9%, in comparison to subjects with no consumption of orange juice (NS). Furthermore, NL and HL – CS groups showed a tendency for low LDL-C/HDL-C ratio, respectively 13% and 14%. Homocysteine was not different between NL - CS and HL - CS groups. Dietary intake of energy, protein and carbohydrate was according to nutritional allowances (DRI) in the NL e HL subjects. In addition, large consumption of saturated fatty acid and dietary cholesterol were associated with overweight, obesity and hyperlipemia in this population. Finally, orange juice consumption was associated with lower levels of blood lipids in NL and HL subjects, and suggests a protector role against the coronary heart disease.
Descrição
Palavras-chave
Suco de laranja, Lídides séricos, Coronariopatias - Homens
Como citar
BONIFÁCIO, Nancy Preising Aptekmann. Influência do consumo de suco de laranja no perfil sérico dos lípides, apolipoproteínas e homocisteína em homens normais e hiperlipidêmicos. 2007. 88 f. Tese (doutorado) - Univesidade Estadual Paulista, Faculdade de Ciências Farmacêuticas, 2007.