Publicação: Silver colloidal nanoparticle stability: influence on Candida biofilms formed on denture acrylic
Nenhuma Miniatura disponível
Data
2014-08-01
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Informa Healthcare
Tipo
Artigo
Direito de acesso
Acesso restrito
Resumo
Our aim in this study was to evaluate how the chemical stability of silver nanoparticles (SNs) influences their efficacy against Candida albicans and C. glabrata biofilms. Several parameters of SN stability were tested, namely, temperature (50 degrees C, 70 degrees C, and 100 degrees C), pH (5.0 and 9.0), and time of contact (5 h and 24 h) with biofilms. The control was defined as SNs without temperature treatment, pH 7, and 24 h of contact. These colloidal suspensions at 54 mg/L were used to treat mature Candida biofilms (48 h) formed on acrylic. Their efficacy was determined by total biomass and colony-forming unit quantification. Data were analyzed using analysis of variance and the Bonferroni post hoc test (alpha = 0.05). The temperature and pH variations of SNs did not affect their efficacy against the viable cells of Candida biofilms (P > 0.05). Moreover, the treatment periods were not decisive in terms of the susceptibility of Candida biofilms to SNs. These findings provide an important advantage of SNs that may be useful in the treatment of Candida-associated denture stomatitis.
Descrição
Palavras-chave
Idioma
Inglês
Como citar
Medical Mycology. London: Informa Healthcare, v. 52, n. 6, p. 627-635, 2014.
