Seasonal variability in the fertilization rate of women undergoing assisted reproduction treatments
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Data
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Coorientador
Pós-graduação
Curso de graduação
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ISSN da Revista
Título de Volume
Editor
Informa Healthcare
Tipo
Artigo
Direito de acesso
Acesso restrito
Resumo
The objective of this study was to evaluate whether seasonality affects human-assisted reproduction treatment outcomes. For this, 1932 patients undergoing intracytoplasmic sperm injection (ICSI) were assigned to a season group according to the day of oocyte retrieval: winter (n = 435), spring (n = 444), summer (n = 469) or autumn (n = 584). Analysis of variance was used to compare the ICSI outcomes. The fertilization rate was increased during the spring (winter: 67.9%, spring: 73.5%, summer: 68.7% and autumn: 69.0%; p < 0.01). In fact, a nearly 50% increase in the fertilization rate during the spring was observed (odds ratio 1.45, confidence interval 1.20-1.75; p < 0.01). The oestradiol concentration per number of oocytes was significantly higher during the spring (winter: 235.8 pg/mL, spring: 282.1 pg/mL, summer: 226.1 pg/mL and autumn: 228.7 pg/mL; p = 0.030). This study demonstrates a seasonal variability in fertilization after ICSI, where fertilization is higher during the spring than at any other time.
Descrição
Palavras-chave
Fertilization, ICSI, oestradiol, photoperiod, seasonality
Idioma
Inglês
Citação
Gynecological Endocrinology. New York: Informa Healthcare, v. 28, n. 7, p. 549-552, 2012.
