Electrochemical investigation of the voltammetric determination of hydrochlorothiazide using a nickel hydroxide modified nickel electrode
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Data
2015-12-01
Autores
Machini, Wesley B. S. [UNESP]
David-Parra, Diego N. [UNESP]
Teixeira, Marcos F. S. [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Elsevier B. V.
Resumo
The preparation and electrochemical characterization of a nickel hydroxide modified nickel electrode as well as its behavior as electrocatalyst toward the oxidation of hydrochlorothiazide (HCTZ) were investigated. The electrochemical behavior of the modified electrode and the electrooxidation of HCTZ were explored using cyclic voltammetry. The voltammetric response of the modified electrode in the detection of HCTZ is based on the electrochemical oxidation of the Ni(II)/Ni(III) and a chemical redox process. The analytical parameters for the electrooxidation of HCTZ by the nickel hydroxide modified nickel electrode were obtained in NaOH solution, in which the linear voltammetric response was in the concentration range from 1.39×10(-5) to 1.67×10(-4)molL(-1) with a limit of detection of 7.92×10(-6)molL(-1) and a sensitivity of 0.138μALmmol(-1). Tafel analysis was used to elucidate the kinetics and mechanism of HCTZ oxidation by the modified electrode.
Descrição
Palavras-chave
Electrocatalyst sensor, Electrochemical behavior, Hydrochlorothiazide, Modified nickel electrode, Voltammetric determination
Como citar
Materials Science & Engineering. C, Materials For Biological Applications, v. 57, p. 344-348, 2015.