Modelos lineares generalizados bayesianos para dados longitudinais
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Data
2016-02-19
Autores
Monfardini, Frederico [UNESP]
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Universidade Estadual Paulista (Unesp)
Resumo
Os Modelos Lineares Generalizados (GLM) foram introduzidos no início dos anos 70, tendo um grande impacto no desenvolvimento da teoria estatística. Do ponto de vista teórico, esta classe de modelos representa uma abordagem unificada de muitos modelos estatísticos, correntemente usados nas aplicações, podendo-se utilizar dos mesmos procedimentos de inferência. Com o avanço computacional das últimas décadas foi notável o desenvolvimento de extensões nesta classe de modelos e de métodos para os procedimentos de inferência. No contexto da abordagem Bayesiana, até a década de 80 utilizava-se de métodos aproximados de inferência, tais como aproximação de Laplace, quadratura Gaussiana e outros. No início da década de 90, foram popularizados os métodos de Monte Carlo via Cadeias de Markov (Monte Carlo Markov Chain - MCMC) que revolucionaram as aplicações no contexto Bayesiano. Apesar de serem métodos altamente eficientes, a convergência do algoritmo em modelos complexos pode ser extremamente lenta, o que gera alto custo computacional. Em 2009 surgiu o método de Aproximações de Laplace Aninhadas Integradas (Integrated Nested Laplace Aproximation - INLA) que busca eficiência tanto no custo computacional como na precisão das estimativas. Considerando a importância desta classe de modelos, neste trabalho propõem-se explorar extensões dos MLG para dados longitudinais e recentes propostas apresentadas na literatura para os procedimentos de inferência. Mais especificamente, explorar modelos para dados binários (binomiais) e para dados de contagem (Poisson), considerando a presença de variabilidade extra, incluindo superdispersão e presença de efeitos aleatórios através de modelos hierárquicos e modelos hierárquicos dinâmicos. Além disso, explorar diferentes procedimentos de inferência no contexto Bayesiano, incluindo MCMC e INLA.
Generalized Linear Models (GLM) were introduced in the early 70s, having a great impact on the development of statistical theory. From a theoretical point of view, this class of model is a unified approach to many statistical models commonly used in applications and can be used with the same inference procedures. With advances in the computer over subsequent decades has come a remarkable development of extensions in this class of design and method for inference procedures. In the context of Bayesian approach, until the 80s, it was used to approximate inference methods, such as approximation of Laplace, Gaussian quadrature, etc., The Monte Carlo Markov Chain methods (MCMC) were popularized in the early 90s and have revolutionized applications in a Bayesian context. Although they are highly efficient methods, the convergence of the algorithm in complex models can be extremely slow, which causes high computational cost. The Integrated Nested Laplace Approximations method (INLA), seeking efficiency in both computational cost and accuracy of estimates, appeared in 2009. This work proposes to explore extensions of GLM for longitudinal data considering the importance of this class of model, and recent proposals in the literature for inference procedures. More specifically, it explores models for binary data (binomial) and count data (Poisson), considering the presence of extra variability, including overdispersion and the presence of random effects through hierarchical models and hierarchical dynamic models. It also explores different Bayesian inference procedures in this context, including MCMC and INLA.
Generalized Linear Models (GLM) were introduced in the early 70s, having a great impact on the development of statistical theory. From a theoretical point of view, this class of model is a unified approach to many statistical models commonly used in applications and can be used with the same inference procedures. With advances in the computer over subsequent decades has come a remarkable development of extensions in this class of design and method for inference procedures. In the context of Bayesian approach, until the 80s, it was used to approximate inference methods, such as approximation of Laplace, Gaussian quadrature, etc., The Monte Carlo Markov Chain methods (MCMC) were popularized in the early 90s and have revolutionized applications in a Bayesian context. Although they are highly efficient methods, the convergence of the algorithm in complex models can be extremely slow, which causes high computational cost. The Integrated Nested Laplace Approximations method (INLA), seeking efficiency in both computational cost and accuracy of estimates, appeared in 2009. This work proposes to explore extensions of GLM for longitudinal data considering the importance of this class of model, and recent proposals in the literature for inference procedures. More specifically, it explores models for binary data (binomial) and count data (Poisson), considering the presence of extra variability, including overdispersion and the presence of random effects through hierarchical models and hierarchical dynamic models. It also explores different Bayesian inference procedures in this context, including MCMC and INLA.
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Modelos lineares generalizados, Modelos hierárquicos dinâmicos, MCMC, INLA, Generalized linear models, Hierarchical dynamic models