Crystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A(2) complexed with alpha-tocopherol
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Bentham Science Publ Ltd
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Resumo
BnSP-7 and BnSP-6, two Lys49-phospholipase A(2) isolated from Bothrops neuwiedi pauloensis snake venom, were co-crystallized with a-tocopherol and X-ray diffraction data were collected for both complexes (2.2 and 2.6 angstrom). A new alternative quaternary conformation for these two complexes compared with all other dimeric Lys49-PLA(2) has been observed.
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crystallization, X-ray crystallography, Lys49-phospholipase A(2), Bothrops neuwiedi venom, myotoxity, alpha-tocopherol
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Inglês
Citação
Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 12, n. 8, p. 819-822, 2005.
