Crystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A(2) complexed with alpha-tocopherol
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Data
2005-11-01
Autores
dos Santos, J. I.
Takeda, AAS
Marchi-Salvador, D. P.
Soares, A. M.
Fontes, MRM
Título da Revista
ISSN da Revista
Título de Volume
Editor
Bentham Science Publ Ltd
Resumo
BnSP-7 and BnSP-6, two Lys49-phospholipase A(2) isolated from Bothrops neuwiedi pauloensis snake venom, were co-crystallized with a-tocopherol and X-ray diffraction data were collected for both complexes (2.2 and 2.6 angstrom). A new alternative quaternary conformation for these two complexes compared with all other dimeric Lys49-PLA(2) has been observed.
Descrição
Palavras-chave
crystallization, X-ray crystallography, Lys49-phospholipase A(2), Bothrops neuwiedi venom, myotoxity, alpha-tocopherol
Como citar
Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 12, n. 8, p. 819-822, 2005.