Brown Recluse Spider Venom: Proteomic Analysis and Proposal of a Putative Mechanism of Action
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Data
2009-08-01
Autores
dos Santos, Lucilene D. [UNESP]
Dias, Nathalia B. [UNESP]
Pinto, Jose Roberto. A. S. [UNESP]
Palma, Mario Sergio [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Bentham Science Publ Ltd
Resumo
Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures.
Descrição
Palavras-chave
Proteomic analysis, spider venom, MudPIT, mass spectrometry, mechanism of action
Como citar
Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 8, p. 933-943, 2009.