Mapping the BDA20 Gene to BTAX
Carregando...
Fonte externa
Fonte externa
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Karger
Tipo
Trabalho apresentado em evento
Direito de acesso
Acesso aberto
Fonte externa
Fonte externa
Resumo
The lipocalin family is a large group of proteins that exhibits great structural and functional variation both within and among species, including a significant number of animal-derived aeroallergens, such as the bovine BDA20 (major cow dander allergen). This protein is classified as an occupational allergen causing asthma and other work-related allergic disorders among dairy farmers. Using a somatic cell panel the BDA20 gene was assigned to the bovine X chromosome (BTAX) with a significant concordant value of 97% to the previously mapped reference marker MAF45. A radiation hybrid (RH) mapping approach confirmed the assignment of BDA20 to BTAX. Two-point LOD scores showed that BDA20 is linked to XBM451 with a LOD score of 22.1 for a 0 value of 0.03.
Descrição
Palavras-chave
BTAX, major cow dander allergen, X chromosome, BDA20
Idioma
Inglês
Citação
Animal Genomics For Animal Health. Basel: Karger, v. 132, p. 359-361, 2008.
