Determinação espectrofotométrica de hexametilenotetramina (HMT) em medicamentos, utilizando ácido cromotrópico e forno de micro-ondas
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Data
2009-01-01
Autores
Fagnani, Enelton
Pezza, Leonardo [UNESP]
Pezza, Helena Redigolo [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Sociedade Brasileira de Química
Resumo
This paper proposes a methodology for spectrophotometric determination of hexamethylenetetramine (HMT) by using chromotropic acid in a phosphoric acid media employing a domestic microwave oven as a source of heating. The reddish-purple soluble product is quantitatively formed after 30 s of irradiation and obeys the Beer´s law in the range between 0.1-1.2 mg L-1 HMT (r = 0.99925). The method was applied successfully in commercial pharmaceutical preparations containing dyes in their composition. The results showed that the method proposed is feasible for simplicity, speed, low cost, precision and accuracy when compared with United States Pharmacopeia official method.
Descrição
Palavras-chave
hexamethylenetetramine, chromotropic acid, microwave oven
Como citar
Química Nova. Sociedade Brasileira de Química, v. 32, n. 9, p. 2458-2463, 2009.