ASPECTOS PATOLÓGICOS da INTOXICAÇÃO DE SUÍNOS POR SEMENTES DE Crotalaria spectabilis (Fabaceae)
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Data
1997-01-01
Autores
Souza, Adriana Coelho de [UNESP]
Hatayde, Mario Roberto [UNESP]
Bechara, Gervasio Henrique [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Colégio Brasileiro de Patologia Animal - CBPA
Resumo
Foram utilizados 24 suínos desmamados, distribuídos em quatro tratamentos, com seis animais em cada. Os suínos dos tratamentos 1, 2, 3 e 4 receberam, durante 90 dias, ração com respectivamente: 0,0, 0,2, 0,4 e 0,6% de sementes de Crotalaria spectabilis. Os animais que morreram durante o período experimental foram necropsiados logo após a morte. Os sobreviventes foram sacrificados no último dia do experimento. Durante as necropsias, foram colhidos fragmentos do fígado, rim, pulmão e estômago, para realização de exame histopatológico. Os principais sintomas da intoxicação foram edemas subcutâneos, principalmente nos membros, na face e região do pescoço, mucosas oral e ocular pálidas, cerdas eriçadas, caquexia e apatia. O hidropericárdio foi a lesão macroscópica mais comum, acometendo vários animais que receberam a ração contaminada. As principais lesões microscópicas foram fibrose, proliferação de ductos biliares e megalocitose no fígado, broncopneumonia e bronquite crônicas, megalocitose de células epiteliais tubulares renais, nefrose e nefrite crônica, bem como gastrite e ulceração gástrica. Os resultados destes experimentos indicam que ração contaminada com sementes de C. spectabilis, nas proporções utilizadas, foi tóxica para suínos.
A feeding experiment was undertaken using 24 weanling pigs, distributed in four treatments, with 6 animals in each group. The animals of group 1, 2, 3 and 4 were fed with rations containing 0.0, 0.2, 0.4 and 0.6% of Crotalaria spectabilis seeds, respectively, during a period of 90 days. Postmorten examination was performed immediately after death in the animals which died during the experiment. The pigs which survived were sacrificed on the last day of the experiment. During the autopsy fragments of liver, kidneys, lungs and stomach were collected for histological examination. The main clinical signs of the intoxication were subcutaneous oedema, affecting particulary the face, limbs and neck, pale ocular and oral mucous membranes, ruffled bristle, emaciation and apathy. Hydropericardium was the most common finding at necropsy, occurring in several intoxicated animals. The major microscopic changes were fibrosis, bile ductulus proliferation and megalocytosis in the liver, bronchopneumonia and chronic bronchitis, renal tubular cell megalocytosis, nephrosis and chronic nephritis, as well as gastritis and gastric ulcerations. The experimental findings showed that rations contaminated with C. spectabilis seeds, at the used rate, were toxic to swine.
A feeding experiment was undertaken using 24 weanling pigs, distributed in four treatments, with 6 animals in each group. The animals of group 1, 2, 3 and 4 were fed with rations containing 0.0, 0.2, 0.4 and 0.6% of Crotalaria spectabilis seeds, respectively, during a period of 90 days. Postmorten examination was performed immediately after death in the animals which died during the experiment. The pigs which survived were sacrificed on the last day of the experiment. During the autopsy fragments of liver, kidneys, lungs and stomach were collected for histological examination. The main clinical signs of the intoxication were subcutaneous oedema, affecting particulary the face, limbs and neck, pale ocular and oral mucous membranes, ruffled bristle, emaciation and apathy. Hydropericardium was the most common finding at necropsy, occurring in several intoxicated animals. The major microscopic changes were fibrosis, bile ductulus proliferation and megalocytosis in the liver, bronchopneumonia and chronic bronchitis, renal tubular cell megalocytosis, nephrosis and chronic nephritis, as well as gastritis and gastric ulcerations. The experimental findings showed that rations contaminated with C. spectabilis seeds, at the used rate, were toxic to swine.
Descrição
Palavras-chave
Poisonous plants, Crotalaria spectabilis, experimental poisoning, swine pathology, Plantas tóxicas, Crotalaria spectabilis, Intoxicação experimental, Suíno, Patologia
Como citar
Pesquisa Veterinária Brasileira. Colégio Brasileiro de Patologia Animal - CBPA, v. 17, n. 1, p. 12-18, 1997.