Eficácia anti-helmíntica comparativa da associação albendazole, levamisole e ivermectina à moxidectina em ovinos
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Data
2007-06-01
Autores
Buzzulini, Carolina [UNESP]
Silva Sobrinho, Américo Garcia da [UNESP]
Costa, Alvimar José da [UNESP]
Santos, Thaís Rabelo dos [UNESP]
Borges, Fernando de Almeida [UNESP]
Soares, Vando Edésio
Título da Revista
ISSN da Revista
Título de Volume
Editor
Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
Resumo
Avaliou-se a eficácia anti-helmíntica da associação de albendazole 2,0%, cloridrato de levamisole 2,55% e ivermectina 0,08% comparativamente à moxidectina 1% em ovinos naturalmente infectados. Foram selecionados 24 ovinos para a composição de três grupos experimentais com oito animais cada: T1, ovinos tratados com a associação albendazole, levamisole e ivermectina, na dosagem de 1 mL 4 kg-1 de peso corporal; T2, ovinos tratados com moxidectina, na dosagem de 1 mL 50 kg-1 de peso corporal e T3, ovinos sem tratamento anti-helmíntico. Foram realizadas contagens de ovos por grama de fezes (OPG) no primeiro, terceiro, quinto e sétimo dia após os tratamentos. No sétimo dia todos os ovinos foram necropsiados e todos os helmintos encontrados no trato gastrintestinal foram quantificados e identificados quanto ao gênero e à espécie. A associação dos diferentes princípios ativos foi 100% eficaz no combate às espécies Cooperia punctata, C. pectinata, C. spatulata, Trichostrongylus axei, Oesophagostomum columbianum, Trichuris ovis, C. curticei e Strongyloides papillosus e, a moxidectina eliminou as seis primeiras espécies citadas. Contra Haemonchus contortus a associação apresentou eficácia superior (93%) à moxidectina (51,4%). Ambas formulações foram eficazes contra Trichostrongylus colubriformis. A associação medicamentosa utilizada constitui alternativa no controle das nematodioses ovinas.
The anthelmintic efficacy of 2.0% albendazol, 2.55% levamisol chloridrate and 0.08% ivermectin formulation to 1% moxidectin in sheep naturally infected with gastrointestinal nematodes was compared. Twenty-four animals were selected by faecal egg counts (FEC) means, composing three experimental groups with eight sheep each: T1, sheep treated with albendazol, levamisol and ivermectin association; T2, sheep treated with 1% moxidectin and T3, untreated group. FEC was estimated at 1st, 3rd, 5th and 7th day post-treatment. All animals were slaughtered at 7th day post-treatment to quantify and identify the nematode burden. The association was 100% effective against eight of ten helminth species (Cooperia punctata, C. pectinata, C. curticei, C. spatulata, Strongyloides papillosus, Trichostrongylus axei, Oesophagostomum columbianum and Trichuris ovis), while the moxidectin removed only six of these species. It also had superior efficacy against Haemonchus contortus (93%) when compared to the 1% moxidectin (51.4%). Both formulations showed similar efficacy against Trichostrongylus colubriformis. Therefore, the anthelmintic association can be an alternative on sheep nematodiosis control.
The anthelmintic efficacy of 2.0% albendazol, 2.55% levamisol chloridrate and 0.08% ivermectin formulation to 1% moxidectin in sheep naturally infected with gastrointestinal nematodes was compared. Twenty-four animals were selected by faecal egg counts (FEC) means, composing three experimental groups with eight sheep each: T1, sheep treated with albendazol, levamisol and ivermectin association; T2, sheep treated with 1% moxidectin and T3, untreated group. FEC was estimated at 1st, 3rd, 5th and 7th day post-treatment. All animals were slaughtered at 7th day post-treatment to quantify and identify the nematode burden. The association was 100% effective against eight of ten helminth species (Cooperia punctata, C. pectinata, C. curticei, C. spatulata, Strongyloides papillosus, Trichostrongylus axei, Oesophagostomum columbianum and Trichuris ovis), while the moxidectin removed only six of these species. It also had superior efficacy against Haemonchus contortus (93%) when compared to the 1% moxidectin (51.4%). Both formulations showed similar efficacy against Trichostrongylus colubriformis. Therefore, the anthelmintic association can be an alternative on sheep nematodiosis control.
Descrição
Palavras-chave
anthelminthics, Control, sheep nematodiosis, anti-helmínticos, Controle, nematodiose ovina
Como citar
Pesquisa Agropecuária Brasileira. Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA) Informação TecnológicaPesquisa Agropecuária Brasileira, v. 42, n. 6, p. 891-895, 2007.