Publicação: An improved electrophoretic method for a screening program for haemoglobinopathies
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Resumo
A method for a screening program for haemoglobinopathies in a starch agar gel mixed with saponin is presented. Normal and abnormal blood containing haemoglobins S, C, I, M Boston, D Punjab, beta thalassaemia major and beta thalassaemia minor, were applied, in a tray with the capacity for 100 samples. The electrophoresis was performed in 45 min using 300 V. This method offers special advantages for the examination of a large number of samples, using a small amount of whole blood and without the previous preparation of haemoglobin solution.
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blood and hemopoietic system, hemoglobinopathy, methodology, Electrophoresis, Agar Gel, Hemoglobin C, Hemoglobin M, Hemoglobin, Sickle, Hemoglobinopathies, Hemoglobins, Hemoglobins, Abnormal, Saponins, Thalassemia
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Inglês
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Experientia, v. 36, n. 7, p. 875-876, 1980.
