Publicação: Adenocarcinoma de cólon com diferenciação neuro-endócrina e escamosa. Relato de caso.
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Resumo
A tubular adenocarcinoma of the colon with solid area composed by small cells that was found by immunohistochemistry study using antibody to neuron-specific enolase (NSE) to possess neuroendocrine differentiation is related. In another areas of the tumor were visualized keratinizing squamous cells. The presence of neuro-endocrine and squamous cells features provide further evidence that neoplastic colonic cells have the capacity for multi-directional differentiation. The implications of this combination in relation to theories of tumor origin and differentiation and the prognostic significance of neuro-endocrine cells in malignant neoplasms of the gastrointestinal tract are discussed.
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adenocarcinoma, aged, case report, cell differentiation, colon tumor, female, human, immunohistochemistry, neurosecretion, pathology, squamous cell carcinoma, Adenocarcinoma, Aged, Carcinoma, Squamous Cell, Case Report, Cell Differentiation, Colonic Neoplasms, English Abstract, Female, Human, Immunohistochemistry, Neurosecretory Systems
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Português
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Arquivos de Gastroenterologia, v. 29, n. 2, p. 62-65, 1992.
