Resposta metabólica de pacientes cirróticos (Child A) ao aumento da ingestão protéica e/ou calórica. Estudo do balanço nitrogenado.
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Data
1992-10-01
Autores
Dichi, J. B.
Dichi, I.
Papini-Berto, S. J.
Bicudo, M. H.
Angeleli, A. Y.
Rezende, T. A.
Burini, Roberto Carlos [UNESP]
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Resumo
The dietary protein assimilation by cirrhotic undernourished patients (lower lean body mass and plasma TBPA and RBP levels) was investigated in five-adult male subjects suffering from histologically diagnosed liver cirrhosis, in its clinically mild stage (Child-Turcotte-Pugh grade A). During the 9 day-dietary study the patients received orally a sequence of complete-regional diets containing different protein-energy compositions identified as (g prot/Cal/kg/day): D0 = 0.42/20.9; D1 = 0.91/37.5; D2 = 0.99/47.9 and D3 = 1.60/40.5. The respective N-balance values (g/day) found were (mean +/- SD): low protein calorie (D0) = -4.24 +/- 2.46; normal protein calorie (D1) = 0.66 +/- 1.99; normal protein-high calorie (D2) = 1.14 +/- 2.54; high protein normal calorie (D3) = 5.12 +/- 2.48. The correspondent urea-N output (g/kg/day) were D0 = 0.22 +/- 0.100; D1 = 0.238 +/- 0.099; D = 0.20 +/- 0.063 and D3 = 0.310 +/- 0.121. The present data thus suggest that protein rather than energy intake would be the limited factor for increasing the N-retention in (mild) cirrhotic patients whom tolerate well dietary protein at either normal or elevated levels.
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Palavras-chave
nitrogen, adult, body mass, diet therapy, epidemiology, human, liver cirrhosis, male, metabolism, nutritional status, protein intake, Adult, Body Mass Index, Dietary Proteins, English Abstract, Human, Liver Cirrhosis, Male, Middle Age, Nitrogen, Nutritional Status, Sampling Studies
Como citar
Arquivos de Gastroenterologia, v. 29, n. 4, p. 128-136, 1992.