COMPARACAO ENTRE MEDICAMENTOS ORAIS ATRAVES DAS TAXAS SERICAS DE GLICOSE, AMILASE, ACIDOS GRAXOS LIVRES E LIPOPROTEINAS DE ALTA DENSIDADE (HDL-COLESTEROL) NOS DIABETICOS DE AMBOS OS SEXOS, DA REGIAO DE ARARAQUARA, NAO-DEPENDENTES DE INSULINA
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Data
1993-12-01
Autores
Pepato, Maria Teresa [UNESP]
Brunetti, Iguatemy Lourenço [UNESP]
Lourenzoni, A. O. [UNESP]
Fonseca, Luiz Marcos da [UNESP]
Vendramini, R. [UNESP]
Accetozi, M. [UNESP]
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Resumo
A study was carried out, on both sexes, to determine the effects of chlorpropamide (DIABINESE) and glibenclamide (DAONIL) on patients with Type II diabetes using as metabolic parameters the following serum: glucose, amilase, high density lipoprotein cholesterol, free fatty acids. The results indicated that both drugs were potentially similar in relation to glycemia, high density lipoprotein cholesterol, and free fatty acids, in both sexes. Chlorpropamide was significantly more effective in reducing amilase activity in male diabetics than glibenclamide. The above mentioned hypoglycemiants did not reduce glycemia to basic levels in either masculine or feminine groups of diabetics.
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Palavras-chave
amilase, chlorpropamide, free fatty acids, glibenclamide, glycemia, high density lipoprotein cholesterol, non insulin dependent diabetics, amylase, fatty acid, glucose, adult, aged, clinical trial, controlled clinical trial, controlled study, drug effect, female, human, major clinical study, male, metabolic parameters, non insulin dependent diabetes mellitus, oral drug administration
Como citar
Revista de Ciencias Farmaceuticas, v. 15, p. 85-94.