Immunohistochemical characterisation of probable intravascular haematopoiesis in the vasa rectae of the renal medulla in acute tubular necrosis
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Immunohistochemistry was applied to identify the nature of the nucleated cells that accumulate in the vasa rectae of the corticomedullary junction in acute tubular necrosis. In all 6 cases studied, there were intravascular cells that reacted with monoclonal antibodies to erythroblast, macrophages, myeloid cells, T and B lymphocytes and rare megakaryocytes. The findings are consistent with the occurrence of intravascular haematopoiesis in the renal medulia in acute tubular necrosis.
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Acute tubular necrosis, Haematopoiesis, Immunohistochemistry, Kidney, acute kidney tubule necrosis, adult, aged, b lymphocyte, bone marrow cell, clinical article, erythroblast, female, hematopoiesis, human, human tissue, immunohistochemistry, kidney blood vessel, kidney medulla, macrophage, megakaryocyte, t lymphocyte, Adult, Aged, Arterioles, Female, Hematopoiesis, Extramedullary, Human, Immunoenzyme Techniques, Kidney Medulla, Kidney Tubular Necrosis, Acute, Middle Age
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Pathology Research and Practice, v. 190, n. 11, p. 1066-1070, 1994.