Heat shock proteins (HSP): dermatological implications and perspectives
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Data
2012-01-01
Autores
Magalhaesi, Wagner Vidal
Nogueira, Marcelo Fábio Gouveia [UNESP]
Kaneko, Telma Mary
Título da Revista
ISSN da Revista
Título de Volume
Editor
John Libbey Eurotext Ltd
Resumo
In recent years, several studies have demonstrated the protective effect of Heat Shock Proteins (HSP) on different organs and tissues under stressful conditions. However, most research explores the performance of those molecular chaperones during immune responses or pathological conditions like cancer, whereas the number of studies related to the performance of HSPs in the skin during diverse natural or physiopathological conditions is very low. Therefore, the aim of this article was to summarize the main concepts concerning the expression and performance of HSPs, from analysis of current medicine and cosmetics publications, as well as exploring the importance of these proteins in the dermatological area in physiological events such as cutaneous aging, skin cancer and wound healing and to present final considerations related to biotechnology performance in this area.
Descrição
Palavras-chave
heat-shock proteins, skin, gene expression, skin manifestations, prevention and control
Como citar
European Journal of Dermatology. Montrouge: John Libbey Eurotext Ltd, v. 22, n. 1, p. 8-13, 2012.