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Communiols E-H: New polyketide metabolites from the coprophilous fungus Podospora communis

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Communiols E-H (1-4), four new polyketide-derived natural products containing furanocyclopentane, furanocyclopentene, cyclopentene, or γ-lactone moieties, have been isolated from two geographically distinct isolates of the coprophilous fungus Podospora communis. The structures of these compounds were determined by analysis of NMR and MS data. © 2005 American Chemical Society and American Society of Pharmacognosy.

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cyclopentane derivative, furan derivative, lactone, antifungal agent, antiinfective agent, communiol A, communiol B, communiol C, communiol D, communiol E, communiol F, communiol G, communiol H, cyclopentene derivative, furanocyclopentane derivative, furanocyclopentene derivative, gamma lactone derivative, natural product, polyketide, unclassified drug, chemical structure, chemistry, Ecuador, isolation and purification, mass spectrometry, nuclear magnetic resonance, Podospora, United States, antibacterial activity, antifungal activity, Bacillus subtilis, Candida albicans, carbon nuclear magnetic resonance, drug isolation, drug structure, fungus culture, fungus isolation, nonhuman, nuclear magnetic resonance spectroscopy, nuclear Overhauser effect, Podospora communis, proton nuclear magnetic resonance, Staphylococcus aureus, stereochemistry, structure analysis, California, Cyclopentanes, Furans, Lactones, Mass Spectrometry, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Coprophilous, Fungi

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Inglês

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Journal of Natural Products, v. 68, n. 3, p. 435-438, 2005.

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