Publicação: Effect of the association of nystatin with a tissue conditioner on its ultimate tensile strength
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Data
2006-09-01
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Purpose: This study evaluated the ultimate tensile strength of a tissue conditioner without nystatin incorporation (GI - control group) and the same tissue conditioner modified by the addition of nystatin in two concentrations: GII - 500,000 International Units (U) and GIII - 1,000,000 U, in which each milligram of the medicament corresponded to 6079 U. Materials and Methods: Dumbbell-shaped specimens (N = 7) with a central cross-sectional area of 33 × 6 × 3 mm were produced for the three experimental groups. After polymerization following manufacturer's instructions, specimens were immersed in distilled water at 37°C for either 24 hours or 7 days and then tested in tension in the MTS 810 at 40 mm/minute. Data were analyzed by two-way ANOVA followed by Tukey's test, at 95% level of confidence. Results: The means (force-grams (gf) ± standard deviation) of the ultimate tensile strength were: GI - 634.29 ± 122.80; GII - 561.92 ± 133.56; and GIII - 547.30 ± 73.47 for 24-hour storage, and GI - 536.68 ± 54.71; GII - 467.50 ± 143.51; and GIII - 500.62 ± 159.76 for 7-day storage. There were no statistically significant differences among the three experimental groups (p > 0.05). The ultimate tensile strength means of all experimental groups after 7 days were significantly lower than those observed after 24 hours (p = 0.04). Conclusions: The results of this study suggest that the addition of nystatin into the tissue conditioner investigated in concentrations below 1,000,000 U did not affect its ultimate tensile strength. Copyright © 2006 by The American College of Prosthodontists.
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Antifungal agent, Candida albicans, Denture stomatitis, UTS, alcohol, antifungal agent, methacrylic acid methyl ester, nystatin, phthalic acid dibutyl ester, plasticizer, analysis of variance, dental care, denture, drug storage, materials testing, reparative dentistry, stomatitis, tensile strength, thrush, time, Analysis of Variance, Antifungal Agents, Candidiasis, Oral, Dental Stress Analysis, Denture Liners, Dibutyl Phthalate, Drug Storage, Ethanol, Materials Testing, Methylmethacrylate, Nystatin, Plasticizers, Stomatitis, Denture, Tensile Strength, Time Factors, Tissue Conditioning (Dental)
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Inglês
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Journal of Prosthodontics, v. 15, n. 5, p. 295-299, 2006.
