MS222 does not induce primary DNA damage in fish
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The genotoxicity of the anaesthetic MS222 (tricaine) was analysed in fish under both in vivo and in vitro conditions. Based on results of the single cell gel/Comet assay, MS222 had no direct genotoxic effect on the experimental fish, indicating that MS222 does not induce primary DNA damage. These results suggest that the use of this important anaesthetic in aquaculture can be considered to be safe in terms of genotoxicity. © Springer Science+Business Media, Inc. 2007.
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Anaesthetic tricaine (ethyl meta-aminobenzoate), DNA damage, Methane sulfonate salt, MS222, Single cell gel (SCG)/Comet assay, Stressful practices in aquaculture, aquaculture, DNA, fish, genotoxicity, methane
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Aquaculture International, v. 15, n. 2, p. 163-168, 2007.
