Clinical and nutritional profile of individuals with Chagas disease

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Data

2007-08-01

Autores

Geraix, Juliana [UNESP]
Ardisson, Lidiane Paula [UNESP]
Marcondes-Machado, Jussara [UNESP]
Pereira, Paulo Câmara Marques [UNESP]

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Resumo

Chagas disease (CD), caused by the protozoan Trypanossoma cruzi, affects approximately 18 million individuals in the Americas, 5 million of which five in Brazil. Most chronic sufferers have either the indeterminate form of the disease, without organic compromise, or the cardiac or digestive forms. Despite the importance of this disease, there is no information on the effect of nutrition on CD evolution. We evaluated the clinical-nutritional profile of individuals with CD treated at the Tropical Diseases Nutrition Out-Patient Clinic of the Botucatu School of Medicine, UNESP.A retrospective cohort study was performed between 2002 and 2006, on 66 patients with serum and parasitological diagnosis of CD. Epidemiological, clinical, nutritional, and biochemical data were collected, including gender, age, skin color, smoking, alcoholism, physical activity, weight, stature, body mass index, abdominal circumference, glycemia, and lipid profile. Fifty-three percent were mate and 47% female; 96% were white skinned. Mean age was 49.6±6.36 years. The predominant form was indeterminate in 71 %; smoking and drinking were recorded in 23% and 17%, respectively. Sedentariness predominated in 83%, and 55% presented increased abdominal circumference. Most, 94%, were overweight or obese. The biochemical exam revealed hyperglycemia in 12% and dyslipidemia in 74%. These findings suggest that the Chagas population presents co-morbidities and risk factors for developing chronic non-transmissible diseases, including cardiovascular diseases, making CD evolution even worse. © 2007 by The Brazilian Journal of Infectious Diseases and Contexto Publishing. All rights reserved.

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Palavras-chave

Chagas disease, Dyslipidemia, Nutrition, glucose, lipid, protozoon antibody, adult, age, alcohol consumption, alcoholism, antibody detection, biochemistry, body build, body mass, body weight, Brazil, cardiovascular disease, cigarette smoking, clinical examination, clinical feature, cohort analysis, comorbidity, controlled study, dyslipidemia, enzyme linked immunosorbent assay, female, glucose blood level, human, hyperglycemia, information processing, major clinical study, male, nutritional assessment, nutritional status, obesity, outpatient department, pathogenesis, physical activity, risk factor, sex difference, skin color, Trypanosoma cruzi, university hospital, Animals, Body Mass Index, Cardiovascular Diseases, Chagas Disease, Chronic Disease, Cohort Studies, Dyslipidemias, Female, Humans, Life Style, Male, Middle Aged, Nutritional Status, Obesity, Retrospective Studies, Risk Factors, Severity of Illness Index

Como citar

Brazilian Journal of Infectious Diseases, v. 11, n. 4, p. 411-414, 2007.