Correlação entre a taxa de fertilização e o fuso meiótico em oócitos humanos: Uma meta-análise
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Objective: To investigate the relationship between the presence of meiotic spindle in human oocytes and fertilization rates in ICSI cycles. Methods: Search strategies included online surveys of databases from 1990 to 2008. Nine trials fulfilled the inclusion criteria Results: According to the meta-analysis, the results showed statistically significant higher fertilization rate (p<0.0001) when the meiotic spindle was viewed than when it was not. There was heterogeneity in this comparison. Conclusion: The presence of a birefringent meiotic spindle in human oocytes can predict a higher fertilization rate. This observation has clinical relevance mainly in countries where there is a legal limit on the number of oocytes to be fertilized. Copyright - SBRA - Sociedade Brasileira de Reprodução Assistida.
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Fertilization rate, Human oocyte, ICSI, Meiotic spindle, Meta-analysis, clinical trial, data analysis, data base, fertilization, human, information retrieval, intracytoplasmic sperm injection, meiosis, meiosis spindle, meta analysis, oocyte, oocyte maturation, systematic review
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Jornal Brasileiro de Reproducao Assistida, v. 13, n. 1, p. 25-28, 2009.
