The in vitro antimicrobial activity of natural infant fluoride-free toothpastes on oral micro-organisms
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Purpose: The objective of this study was to evaluate the antimicrobial activity of six toothpastes for infants: 3 fluoride-free experimental toothpastes - cashew-based, mango-based and without plant extract and fluoride compared with 2 commercially fluoride-free toothpastes and 1 fluoridated toothpastes. Methods: Six toothpastes for infants were evaluated in this study: (1) experimental cashew-based toothpaste; (2) experimental mango-based toothpaste; (3) experimental toothpaste without plant extract and fluoride (negative control); (4) First Teeth brand toothpaste; (5) Weleda brand toothpaste; and (6) Tandy brand toothpaste (positive control). The antimicrobial activity was recorded against Streptococcus mutans, Streptococcus sobrinus, Lactobacillus acidophilus, and Candida albicans using the agar plate diffusion test. Results: First Teeth, Weleda, mango-based toothpaste, and toothpaste without plant extract presented no antimicrobial effect against any of the tested micro-organisms. Cashew toothpaste had antimicrobial activity against S mutans, S sobrinus, and L acidophilus, but it showed no antimicrobial activity against C albicans. There was no statistical difference between the inhibition halo of cashew and Tandy toothpastes against S mutans and L acidophilus. Conclusions: Cashew fluoride-free toothpaste had inhibitory activity against Streptococcus mutans and Lactobacillus acidophilus, and these results were similar to those obtained for fluoridated toothpaste.
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Anarcadium occidentale, Mangifera indica, Plant extracts, Toothpaste, fluoride sodium, plant extract, toothpaste, topical antiinfective agent, Anacardium, analysis of variance, Candida albicans, comparative study, drug effect, human, in vitro study, infant, Lactobacillus acidophilus, Mangifera, microbial sensitivity test, Streptococcus mutans, Streptococcus sobrinus, Analysis of Variance, Anti-Infective Agents, Local, Humans, Infant, Microbial Sensitivity Tests, Plant Extracts, Sodium Fluoride, Toothpastes
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Inglês
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Journal of Dentistry for Children, v. 78, n. 1, p. 3-8, 2011.
