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Dietary, anthropometric, and biochemical determinants of plasma high-density lipoprotein-cholesterol in free-living adults

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The level of high-density lipoprotein is thought to be critical in inhibiting lesion formation as well as reducing the lipid load of preexisting atherosclerotic lesions. With the aim of determining the main determinants of plasma HDL-cholesterol (HDL-c) in free-living adults, 997 individuals (52.3 10 years, 67 females) were selected for a descriptive cross-sectional study. The used data corresponded to the baseline obtained from participants clinically selected for a lifestyle modification program. Covariables of clinical, anthropometry, food intake, aerobic fitness, and plasma biochemistry were analyzed against plasma HDL-c either as continuous or categorized variables. After adjustments for age, gender, and BMI the excess of abdominal fat along with high carbohydrate-energy intake and altered plasma triglycerides were the stronger predictors of reduced plasma HDL-c. In conclusion lifestyle interventions aiming to normalize abdominal fatness and plasma triglycerides are recommended to restore normal levels of HDL-c in these free-living adults. Copyright © 2011 Erick Prado de Oliveira et al.

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glucose, high density lipoprotein cholesterol, triacylglycerol, abdominal fat, abdominal obesity, adult, aerobic exercise, anthropometry, body composition, body mass, caloric intake, carbohydrate intake, cross-sectional study, female, food intake, glucose blood level, human, human experiment, lifestyle modification, male, priority journal, triacylglycerol blood level, waist circumference

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Inglês

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Cholesterol, v. 2011.

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