First defection of the equine herpesvirus 1 neuropathogenic variant in Brazil
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This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G 2254/D 752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A 2254/N 752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil.
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Brazil, DNA polymerase gene, Equine herpesvirus 1, Neurological disease, Neuropathogenic, Equid herpesvirus 1, Equidae, Equine herpesvirus sp., Herpesviridae, Human herpesvirus 1, animal, animal disease, animal euthanasia, brain, case report, Equine herpes virus, fatality, female, genetics, herpes virus infection, horse, horse disease, isolation and purification, myelitis, pathogenicity, pathology, spinal cord, virology, virus encephalitis, Animals, Brain, Encephalitis, Viral, Euthanasia, Animal, Fatal Outcome, Female, Herpesviridae Infections, Herpesvirus 1, Equid, Horse Diseases, Horses, Myelitis, Spinal Cord
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Inglês
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OIE Revue Scientifique et Technique, v. 30, n. 3, p. 949-954, 2011.
