Chemical Composition and Antioxidant and Antimycobacterial Activities of Bromelia balansae (Bromeliaceae)
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Data
2010-10-01
Autores
Coelho, Roberta Gomes
Honda, Neli Kika
Vieira, Maria do Carmo
Brum, Rosenei Louzada
Pavan, Fernando Rogério [UNESP]
Leite, Clarice Queico Fujimura [UNESP]
Lima Cardoso, Claudia Andrea
Título da Revista
ISSN da Revista
Título de Volume
Editor
Mary Ann Liebert, Inc.
Resumo
Bromelia balansae (Family Bromeliaceae) is a medicinal plant commonly used in the central region of Brazil as a cough syrup and also eaten roasted. The methanolic extract of ripe fruits was analyzed by chromatographic methods and spectrometrically. Four glycoside flavonols were isolated: kaempferol-3-O-alpha-l-rhamnopyranoside (1), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-d-glucopyranoside (2), quercetin-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside (3), and kaempferol 3,7-di-O-alpha-L-rhamnopyranoside (4). The resazurin microtiter assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis. The results showed a moderate activity of the methanolic extract with a minimal inhibitory concentration of 128 mu g/mL. Antioxidant activity was evaluated as free radical scavenging capacity and inhibition of peroxidation. Free radical scavenging capacity was assessed by measuring the scavenging activity of methanolic extract and methanolic fraction on 2,2-diphenyl-1-picrylhydrazyl radical. The methanolic extract showed low values of antioxidant activities, whereas the methanolic fraction exhibited free radical scavenging activity ranging from 20.2% to 91.1%, and the inhibition of peroxidation values ranging from 5.6% to 27.5%. This is the first chemical study reported in the literature about this species.
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Palavras-chave
antioxidant activity, antituberculosis activity, Bromelia balansae, Bromeliaceae, caraguata'', flavonols, gravata'', Mycobacterium tuberculosis
Como citar
Journal of Medicinal Food. New Rochelle: Mary Ann Liebert Inc., v. 13, n. 5, p. 1277-1280, 2010.