Publicação: Investigation of genotoxic and antigenotoxic activities of Melampodium divaricatum in Salmonella typhimurium
Carregando...
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Elsevier B.V.
Tipo
Artigo
Direito de acesso
Acesso restrito
Resumo
Melcanpodium divaricatian is a member of the Asteraccae and in Brazil is known as false-calendula, its flowers being used in anti-inflammatory preparations, substituting the true calendula or marigold (Calendula officinalis L.). The flower extract was investigated for mutagenic and antimutagenic effect in the Sahnonella/microsome assay. The tested extract was not mutagenic in the strains TA100, TA98, TA97a and TA102 and decreased the mutagenicity of aflatoxin B1, benzo(a)pyrene and daunomycin. Chlorophyll and triterpenes were detected in the extract, and they might have contributed to the observed effect. Our data suggest that these medicinal plants possess cancer chemopreventive properties. (c) 2005 Elsevier Ltd. All rights reserved.
Descrição
Palavras-chave
Salmonella typhimurium, antimutagenic activity, Melampodium divarication, triterpenes
Idioma
Inglês
Como citar
Toxicology In Vitro. Oxford: Pergamon-Elsevier B.V., v. 20, n. 3, p. 361-366, 2006.
