Prospective study for the development of emulsion systems containing natural oil products
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Arquivos
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Editions Sante
Tipo
Artigo
Direito de acesso
Acesso restrito
Arquivos
Resumo
Copaiba oil, when used as anti-inflammatory and anti-infective agent, presents two major problems: i) low absorption and bioavailability and ii) an unpleasant taste. Once an appropriate emulsion was achieved, the samples were prepared using different surfactant binary mixtures to obtain a range of HLB values between 4.5 and 16.5. The HLB value of copaiba oil was 14.8; this system has been stable for more than one year, and the pseudo-ternary diagrams were useful to describe the component proportions. These results indicated that the copaiba oil emulsion might be a promising vehicle for topical delivery of drugs and active cosmetic ingredients.
Descrição
Palavras-chave
Emulsion, Copaiba oil, Hydrophilic-lipophilic balance, Pseudo-ternary phase diagram, Stability analysis
Idioma
Inglês
Citação
Journal of Drug Delivery Science and Technology. Paris: Editions Sante, v. 22, n. 4, p. 367-372, 2012.
