Publication: Vibrational and Thermal Properties of Crystalline Topiramate
Loading...
Date
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Soc Brasileira Quimica
Type
Article
Access right
Acesso aberto
Abstract
Topiramate, a powerful anticonvulsant drug, was investigated by X-ray diffractometry, FT-Raman, FT-IR, TGA and DTA techniques as well as by DFT calculations. From this study it was possible to tentatively assign most of the normal vibrational modes of the crystal. Thermal analysis from room temperature to 900 degrees C shows that the material does not present any structural phase transition and that the decomposition occurs in a two-step exothermic process.
Description
Keywords
organic crystals, vibrational spectra, X-ray diffraction, thermodynamic properties
Language
English
Citation
Journal of The Brazilian Chemical Society. São Paulo: Soc Brasileira Quimica, v. 19, n. 8, p. 1607-1613, 2008.
