Preparação e caracterização de compósitos polímero/cerâmica com potencial de aplicações médicas
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Data
2001
Autores
Gimenes, Rossano [UNESP]
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Editor
Universidade Estadual Paulista (Unesp)
Resumo
O projeto desenvolvido buscou o estudo sistemáticos de compósitos com potencial de aplicação médica. Pós cerâmicos de Titanato Zirconato de Chumbo dopado com 0,4 mol% de nióbio (PZTN) e Titanato de Bário (BT) foram preparados pelo método Pechini. Utilizou-se também pó de hidroxiapatita de origem comercial (OSTEOSYNTH) Os pós de PZT+0,4mol%Nb e BT foram compactados e sinterizados a 1100ºC/4h. Os compactos sinterizados foram moídos para garantir pós de alta cristalinidade. Foram obtidos filmes compósitos polímero/cerâmica com cerca de 40μm de espessura, pela homogeneização da solução de fluoreto de polivinilideno (PVDF)/dimetil formamida (DMA) com os pós cerâmicos. Os filmes foram depositados pelo espalhamento de solução sobre placa de vidro e também pela técnica spin coating. Também foram obtidos filmes de PVDF puro e do copolímero P(VDF-TrFE) 60/40 mol%. Os filmes foram cristalizados em temperaturas de 70 a 100ºC. As estruturas cristalinas dos filmes foram verificadas por IV e DRX. Resultados de DRX demostraram que filmes de PVDF obtidos por solução cristalizam preferencialmente na fase α. Os filmes de copolímero apresentaram somente uma fase polar. As microestruturas dos compósitos observada por MEV revelaram que o aumento da concentração de cerâmica favorece a formação de aglomerados. Os filmes foram submetidos a polarização pelo método de Rampas de tensão. A polarização ferroelétrica observada para os filmes de P(VDFTrFE)/ BT foi atribuída a otientação dos dipolos na fase ferroelétrica do polímero. Testes de citotoxidade revelaram que o P(VDF-TrFE)/BT 90/10% é um material atoxico. Experimentos in vivo indicaram que o compósito pode induzir o reparo do osso lesado.
The developed project seeks the systematic studies of composites with medical application. Niobiun dopped Lead Titanate Ziconate (PZTN) and Barium Titanate (BT) powders were prepared by Pechini method. Commercial hidroxiapatite powder was used in this project. The PZTN and BT powders were compacted and sintered at 1100 ºC for 4 hours. Sintered compacts were moiled to obtaining powders with high crystallinity. Composites films polymer/ceramic of 40 μm thick were obtained by mixture of poly(nivylidene fluoride)/dimethylacetamide (DMA) solution with ceramic powders. The films were manufactured by spreading of solution onto a glass sheet and also it was obtained by spin coating method. PVDF pure and P(VDF-TrFE) 60/40 %mol copolymer were obtained. The films were crystallized at temperatures ranges from 70ºC at 100ºC. Films structures were verified by IR and XRD analysis. XRD results demonstrated that PVDF films obtained by solution cast it crystallized in the phase α preferably. Only one polar phase was observed for copolymer films. The microstructure of the composites obtained by MEV revealed that an increase in the ceramic concentration favours the formation of agglomerates. The films were poled by ramp voltage method. Electrical polarization was observed to P(VDF-TrFE)/BT films and it was attributed to dipolar alignment in polymer ferroelectric phase. A Citotoxic testis shows that P(VDF-TrFE)/BT 90/10 mol% is an atoxic material. In vivo composite implanted shows that this material can induce bone repair.
The developed project seeks the systematic studies of composites with medical application. Niobiun dopped Lead Titanate Ziconate (PZTN) and Barium Titanate (BT) powders were prepared by Pechini method. Commercial hidroxiapatite powder was used in this project. The PZTN and BT powders were compacted and sintered at 1100 ºC for 4 hours. Sintered compacts were moiled to obtaining powders with high crystallinity. Composites films polymer/ceramic of 40 μm thick were obtained by mixture of poly(nivylidene fluoride)/dimethylacetamide (DMA) solution with ceramic powders. The films were manufactured by spreading of solution onto a glass sheet and also it was obtained by spin coating method. PVDF pure and P(VDF-TrFE) 60/40 %mol copolymer were obtained. The films were crystallized at temperatures ranges from 70ºC at 100ºC. Films structures were verified by IR and XRD analysis. XRD results demonstrated that PVDF films obtained by solution cast it crystallized in the phase α preferably. Only one polar phase was observed for copolymer films. The microstructure of the composites obtained by MEV revealed that an increase in the ceramic concentration favours the formation of agglomerates. The films were poled by ramp voltage method. Electrical polarization was observed to P(VDF-TrFE)/BT films and it was attributed to dipolar alignment in polymer ferroelectric phase. A Citotoxic testis shows that P(VDF-TrFE)/BT 90/10 mol% is an atoxic material. In vivo composite implanted shows that this material can induce bone repair.
Descrição
Palavras-chave
Ceramica, Compositos polimericos, Físico-química - Teses, Ceramic
Como citar
GIMENES, Rossano. Preparação e caracterização de compósitos polímero/cerâmica com potencial de aplicações médicas. 2001. 119 f. Dissertação (mestrado) - Universidade Estadual Paulista, Instituto de Química, 2001.