Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles

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dc.contributor.authorMestieri, Leticia Boldrin [UNESP]
dc.contributor.authorTanomaru-Filho, Mário [UNESP]
dc.contributor.authorGomes-cornélio, Ana Livia [UNESP]
dc.contributor.authorSalles, Loise Pedrosa [UNESP]
dc.contributor.authorBernardi, Maria Inês Basso
dc.contributor.authorGuerreiro-Tanomaru, Juliane Maria [UNESP]
dc.contributor.institutionUniv. Estadual Paulista Araraquara Dental School Department of Restorative Dentistry
dc.contributor.institutionUniversity of São Paulo Institute of Physics
dc.date.accessioned2015-08-06T16:14:48Z
dc.date.available2015-08-06T16:14:48Z
dc.date.issued2014-12-01
dc.description.abstractObjectiveMineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: 1) PC; 2) White MTA; 3) PC+30% Nbµ; 4) PC+30% Nbη. Material and MethodFor the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay. ResultThe results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA. ConclusionIt was concluded that the combination of PC+NbO is a potential alternative for composition of MTA.en
dc.description.affiliationUniv. Estadual Paulista Araraquara Dental School Department of Restorative Dentistry
dc.description.affiliationUniversity of São Paulo Institute of Physics
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent554-559
dc.identifierhttp://dx.doi.org/10.1590/1678-775720140209
dc.identifier.citationJournal of Applied Oral Science. Faculdade De Odontologia De Bauru - USP, v. 22, n. 6, p. 554-559, 2014.
dc.identifier.doi10.1590/1678-775720140209
dc.identifier.fileS1678-77572014000600554.pdf
dc.identifier.issn1678-7757
dc.identifier.scieloS1678-77572014000600554
dc.identifier.urihttp://hdl.handle.net/11449/126198
dc.language.isoeng
dc.publisherFaculdade De Odontologia De Bauru - USP
dc.relation.ispartofJournal of Applied Oral Science
dc.relation.ispartofjcr1.709
dc.relation.ispartofsjr0,645
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectSilicate cementen
dc.subjectNiobiumen
dc.subjectNanotechnologyen
dc.titleRadiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticlesen
dc.typeArtigo
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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