New palladium(II) complexes with pyrazole ligands Part II. Synthesis, spectral and thermal studies, and antitumor evaluation

Página do item simplificado
dc.contributor.authorBarra, Carolina V. [UNESP]
dc.contributor.authorRocha, Fillipe V. [UNESP]
dc.contributor.authorNetto, Adelino Vieira de Godoy [UNESP]
dc.contributor.authorFrem, Regina Célia Galvão [UNESP]
dc.contributor.authorMauro, Antonio Eduardo [UNESP]
dc.contributor.authorCarlos, Iracilda Z. [UNESP]
dc.contributor.authorAnanias, Sandra R. [UNESP]
dc.contributor.authorQuilles, Marcela B. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:23:56Z
dc.date.available2014-05-20T13:23:56Z
dc.date.issued2011-11-01
dc.description.abstractThis study describes the synthesis, IR, (1)H, and (13)C{(1)H} NMR spectroscopic as well the thermal characterization of the new palladium(II) pyrazolyl complexes [PdCl(2)(HmPz)(2)] 1, [PdBr(2)(HmPz)(2)] 2, [PdI(2)(HmPz)(2)] 3, [Pd(SCN)(2)(HmPz)(2)] 4 {HmPz = 4-methylpyrazole}. The residues of the thermal decomposition were identified as Pd(0) by X-ray powder diffraction. From the initial decomposition temperatures, the thermal stability of the complexes can be ordered in the sequence: 1 > 2 > 4 a parts per thousand 3. The cytotoxic activities of the complexes and the ligand were investigated against two murine cancer cell lines: mammary adenocarcinoma (LM3) and lung adenocarcinoma (LP07) and compared to cisplatin under the same experimental conditions.en
dc.description.affiliationUNESP Univ Estadual Paulista, Inst Quim Araraquara, Dept Quim Geral & Inorgan, BR-14801970 Araraquara, SP, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Dept Anal Clin, Fac Ciencias Farmaceut Araraquara, BR-14801902 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Inst Quim Araraquara, Dept Quim Geral & Inorgan, BR-14801970 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Dept Anal Clin, Fac Ciencias Farmaceut Araraquara, BR-14801902 Araraquara, SP, Brazil
dc.format.extent489-494
dc.identifierhttp://dx.doi.org/10.1007/s10973-011-1393-0
dc.identifier.citationJournal of Thermal Analysis and Calorimetry. Dordrecht: Springer, v. 106, n. 2, p. 489-494, 2011.
dc.identifier.doi10.1007/s10973-011-1393-0
dc.identifier.issn1388-6150
dc.identifier.lattes3300223970814448
dc.identifier.lattes7927677053650819
dc.identifier.orcid0000-0002-0057-7964
dc.identifier.urihttp://hdl.handle.net/11449/7312
dc.identifier.wosWOS:000296065100029
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofJournal of Thermal Analysis and Calorimetry
dc.relation.ispartofjcr2.209
dc.relation.ispartofsjr0,587
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectDTAen
dc.subjectPalladium(II)en
dc.subjectPyrazolesen
dc.subjectSpectroscopyen
dc.subjectTGen
dc.titleNew palladium(II) complexes with pyrazole ligands Part II. Synthesis, spectral and thermal studies, and antitumor evaluationen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dcterms.rightsHolderSpringer
unesp.author.lattes3300223970814448[5]
unesp.author.lattes7927677053650819[3]
unesp.author.orcid0000-0002-0057-7964[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Química, Araraquarapt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

Arquivos

Licença do Pacote
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Química Inorgânica - IQ
Artigos - Análises Clínicas - FCFAR