Metabolic syndrome and dietary components are associated with coronary artery disease risk score in free-living adults: a cross-sectional study

dc.contributor.authorTakahashi, Mauro Massao [UNESP]
dc.contributor.authorde Oliveira, Erick Prado [UNESP]
dc.contributor.authorRochitti de Carvalho, Ana Lygia [UNESP]
dc.contributor.authorde Souza Dantas, Lidiane Affonso [UNESP]
dc.contributor.authorPaganini Burini, Franz Homero [UNESP]
dc.contributor.authorMclellan, Katia Cristina Portero [UNESP]
dc.contributor.authorBurini, Roberto Carlos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:38:25Z
dc.date.available2014-05-20T13:38:25Z
dc.date.issued2011-05-09
dc.description.abstractBackground: Coronary artery disease (CAD) is among the main causes of death in developed countries, and diet and lifestyle can influence CAD incidence.Objective: To evaluate the association of coronary artery disease risk score with dietary, anthropometric and biochemical components in adults clinically selected for a lifestyle modification program.Methods: 362 adults (96 men, 266 women, 53.9 +/- 9.4 years) fulfilled the inclusion criteria by presenting all the required data. The Framingham score was calculated and the IV Brazilian Guideline on Dyslipidemia and Prevention of Atherosclerosis was adopted for classification of the CAD risks. Anthropometric assessments included waist circumference (WC), body fat and calculated BMI (kg/m(2)) and muscle-mass index (MMI kg/m(2)). Dietary intake was estimated through 24 h dietary recall. Fasting blood was used for biochemical analysis. Metabolic Syndrome (MS) was diagnosed using NCEP-ATPIII (2001) criteria. Logistic regression was used to determine the odds of CAD risks according to the altered components of MS, dietary, anthropometric, and biochemical components.Results: For a sample with a BMI 28.5 +/- 5.0 kg/m(2) the association with lower risk (<10% CAD) were lower age (<60 years old), and plasma values of uric acid. The presence of MS within low, intermediary, and high CAD risk categories was 30.8%, 55.5%, and 69.8%, respectively. The independent risk factors associated with CAD risk score was MS and uric acid, and the protective factors were recommended intake of saturated fat and fiber and muscle mass index.Conclusion: Recommended intake of saturated fat and dietary fiber, together with proper muscle mass, are inversely associated with CAD risk score. on the other hand, the presence of MS and high plasma uric acid are associated with CAD risk score.en
dc.description.affiliationUNESP Sch Med, Dept Publ Hlth, Ctr Nutr & Phys Exercise Metab, Botucatu, SP, Brazil
dc.description.affiliationUNESP Sch Med UNESP, Botucatu, SP, Brazil
dc.description.affiliationUniv São Paulo, São Paulo, Brazil
dc.description.affiliationUnespUNESP Sch Med, Dept Publ Hlth, Ctr Nutr & Phys Exercise Metab, Botucatu, SP, Brazil
dc.description.affiliationUnespUNESP Sch Med UNESP, Botucatu, SP, Brazil
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent7
dc.identifierhttp://dx.doi.org/10.1186/1758-5996-3-7
dc.identifier.citationDiabetology & Metabolic Syndrome. London: Biomed Central Ltd., v. 3, p. 7, 2011.
dc.identifier.doi10.1186/1758-5996-3-7
dc.identifier.fileWOS000291308200001.pdf
dc.identifier.issn1758-5996
dc.identifier.lattes2287552780901172
dc.identifier.urihttp://hdl.handle.net/11449/13329
dc.identifier.wosWOS:000291308200001
dc.language.isoeng
dc.publisherBiomed Central Ltd.
dc.relation.ispartofDiabetology & Metabolic Syndrome
dc.relation.ispartofjcr2.413
dc.relation.ispartofsjr0,943
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleMetabolic syndrome and dietary components are associated with coronary artery disease risk score in free-living adults: a cross-sectional studyen
dc.typeArtigo
dcterms.licensehttp://www.biomedcentral.com/about/license
dcterms.rightsHolderBiomed Central Ltd.
unesp.author.lattes2287552780901172
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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