Effect of Psidium cattleianum leaf extract on enamel demineralisation and dental biofilm composition in situ

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dc.contributor.authorBrighenti, Fernanda Lourenção [UNESP]
dc.contributor.authorJardim Júnior, Élerson Gaetti [UNESP]
dc.contributor.authorDanelon, Marcelle [UNESP]
dc.contributor.authorEvangelista, Gustavo Vaz [UNESP]
dc.contributor.authorDelbem, Alberto Carlos Botazzo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2013-09-30T18:31:37Z
dc.date.accessioned2014-05-20T13:45:02Z
dc.date.available2013-09-30T18:31:37Z
dc.date.available2014-05-20T13:45:02Z
dc.date.issued2012-08-01
dc.description.abstractObjective: Previous evaluations of Psidium cattleianum leaf extract were not done in conditions similar to the oral environment. The aim of this study was to evaluate the effect of P. cattleianum leaf extract on enamel demineralisation, extracellular polysaccharide formation, and the microbial composition of dental biofilms formed in situ.Design: Ten volunteers took part in this crossover study. They wore palatal appliances containing 4 enamel blocks for 14 days. Each volunteer dripped 20% sucrose 8 times per day on the enamel blocks. Twice a day, deionised water (negative control), extract, or a commercial mouthwash (active control) was dripped after sucrose application. on the 12th and 13th days of the experiment, plaque acidogenicity was measured with a micro-electrode, and the pH drop was calculated. on the 14th day, biofilms were harvested and total anaerobic microorganisms (TM), total streptococci (TS), mutans streptococci (MS), and extracellular polysaccharides (EPS) were evaluated. Enamel demineralisation was evaluated by the percentage change of surface microhardness (%Delta SMH) and integrated loss of subsurface hardness (Delta KHN). The researcher was blinded to the treatments during data collection.Results: The extract group showed lower TM, TS, MS, EPS, %Delta SMH, and Delta KHN values than the negative control group. There were no differences between the active and negative control groups regarding MS and EPS levels. There were no differences in pH drop between the extract and active control groups, although they were significantly different from the negative control group. For all other parameters, the extract differed from the active control group.Conclusion: Psidium cattleianum leaf extract exhibits a potential anticariogenic effect. (C) 2012 Elsevier Ltd. All rights reserved.en
dc.description.affiliationUNESP Univ Estadual Paulista, Aracatuba Dent Sch, BR-16015050 Aracatuba, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Aracatuba Dent Sch, BR-16015050 Aracatuba, SP, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdCAPES: PDEE 4446/05
dc.description.sponsorshipIdCNPq: 471634/2007-7
dc.description.sponsorshipIdFAPESP: 06/00726-8
dc.format.extent1034-1040
dc.identifierhttp://dx.doi.org/10.1016/j.archoralbio.2012.02.009
dc.identifier.citationArchives of Oral Biology. Oxford: Pergamon-Elsevier B.V. Ltd, v. 57, n. 8, p. 1034-1040, 2012.
dc.identifier.doi10.1016/j.archoralbio.2012.02.009
dc.identifier.fileWOS000307797600005.pdf
dc.identifier.issn0003-9969
dc.identifier.lattes4605992512582464
dc.identifier.lattes6065636367717382
dc.identifier.orcid0000-0002-8159-4853
dc.identifier.orcid0000-0002-4470-5171
dc.identifier.urihttp://hdl.handle.net/11449/15805
dc.identifier.wosWOS:000307797600005
dc.language.isoeng
dc.publisherPergamon-Elsevier B.V. Ltd
dc.relation.ispartofArchives of Oral Biology
dc.relation.ispartofjcr2.050
dc.relation.ispartofsjr0,752
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectAntibacterial agentsen
dc.subjectDental cariesen
dc.subjectPlant extracten
dc.titleEffect of Psidium cattleianum leaf extract on enamel demineralisation and dental biofilm composition in situen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderPergamon-Elsevier B.V. Ltd
unesp.author.lattes4605992512582464
unesp.author.lattes0421571920582994[5]
unesp.author.lattes6065636367717382[1]
unesp.author.orcid0000-0002-8159-4853[5]
unesp.author.orcid0000-0002-4470-5171[1]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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Artigos - Patologia e Propedêutica Clínica - FOA