Effect of estrogen therapy, soy isoflavones, and the combination therapy on the submandibular gland of ovariectomized rats

Página do item simplificado
dc.contributor.authorChaves Carvalho, Vinicius Diniz [UNESP]
dc.contributor.authorSarmento Silveira, Vanessa Avila
dc.contributor.authordo Prado, Renata Falchete
dc.contributor.authorCarvalho, Yasmin Rodarte [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFac Pindamonhangaba FAPI
dc.contributor.institutionCruzeiro Super Sch
dc.date.accessioned2014-05-20T14:04:29Z
dc.date.available2014-05-20T14:04:29Z
dc.date.issued2011-01-01
dc.description.abstractThe objective of this study was to evaluate the effect of estrogen deficiency, estrogen therapy, and soy isoflavones on the salivary glands in female rats. Ninety-six animals were ovariectomized, and 24 were sham-operated. Among the ovariectomized rats, 24 received 17 beta-estradiol; 24 received isoflavone extract; 24 received a combination therapy of both; and 24 received water as placebo. The submandibular glands were histomorphometrically analyzed. As a result, the ANOVA test revealed that the hormonal deficiency affected the acini and the ducts of ovariectomized rats, reducing their percentage compared to the sham group. All treatments caused an increase in ducts and acini compared to the placebo group. It was concluded that the estrogen deficiency may be related to salivary gland function due to a reduction in the quantity of salivary acini and ducts secondary to ovariectomy. The estrogen therapy, soy isoflavone therapy, and the combination of both are effective in reducing the effects of ovariectomy on the salivary glands. (c) 2011 Elsevier GmbH. All rights reserved.en
dc.description.affiliationState Univ São Paulo, Sao Jose dos Campos Sch Dent, Dept Biosci & Oral Diag, São Paulo, Brazil
dc.description.affiliationFac Pindamonhangaba FAPI, Anat Lab, São Paulo, Brazil
dc.description.affiliationCruzeiro Super Sch, Dept Physiotherapy, São Paulo, Brazil
dc.description.affiliationUnespState Univ São Paulo, Sao Jose dos Campos Sch Dent, Dept Biosci & Oral Diag, São Paulo, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 07/52746-5R
dc.format.extent300-305
dc.identifierhttp://dx.doi.org/10.1016/j.prp.2011.01.002
dc.identifier.citationPathology Research and Practice. Jena: Elsevier Gmbh, Urban & Fischer Verlag, v. 207, n. 5, p. 300-305, 2011.
dc.identifier.doi10.1016/j.prp.2011.01.002
dc.identifier.issn0344-0338
dc.identifier.lattes6967369119792151
dc.identifier.urihttp://hdl.handle.net/11449/22621
dc.identifier.wosWOS:000291451500006
dc.language.isoeng
dc.publisherElsevier Gmbh, Urban & Fischer Verlag
dc.relation.ispartofPathology Research and Practice
dc.relation.ispartofjcr1.466
dc.relation.ispartofsjr0,547
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectSalivary glandsen
dc.subjectOvariectomyen
dc.subjectEstrogen therapyen
dc.subjectIsoflavonesen
dc.titleEffect of estrogen therapy, soy isoflavones, and the combination therapy on the submandibular gland of ovariectomized ratsen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier Gmbh, Urban & Fischer Verlag
unesp.author.lattes6967369119792151
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia, São José dos Campospt

Arquivos

Licença do Pacote
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Biociências e Diagnóstico Bucal - ICT