Effect of zoledronic acid used in the root surface treatment of late replanted teeth: A study in rats

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dc.contributor.authorMori, Graziela Garrido [UNESP]
dc.contributor.authorJanjacomo, Daniela Maria de Mendonça [UNESP]
dc.contributor.authorNunes, Daniele Clapes [UNESP]
dc.contributor.authorCastilho, Lithiene Ribeiro [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:25:22Z
dc.date.available2014-05-27T11:25:22Z
dc.date.issued2010-12-01
dc.description.abstractThis study evaluated the use of zoledronic acid, a resorption inhibitor, as a medication for root resorption treatment of late replanted teeth. Twenty-four maxillary right central incisors of rats were avulsed and kept dry for 30 min. Then, the teeth were divided into 2 groups. In group I, root surface was treated with 2% sodium fluoride for 20 min; in group II, 10-6M zoledronic acid solution was used for 20 min. All root canals were filled with calcium hydroxide. Next, teeth were replanted in their respective sockets. After 15 and 60 days post-replantation, the animals were killed and the anatomic pieces were obtained and prepared for microscopic and morphometric analyses. The results showed that zoledronic acid was capable of limiting the occurrence of root resorption and preserving cementum resorption. Further research must be performed to confirm the use of zoledronic acid in root surface treatment of late replanted teeth.en
dc.description.affiliationPostgraduate Program in Dentistry Integrated Clinic Area Araçatuba Dental School, São Paulo State University, Araçatuba, S P
dc.description.affiliationUnespPostgraduate Program in Dentistry Integrated Clinic Area Araçatuba Dental School, São Paulo State University, Araçatuba, S P
dc.format.extent452-457
dc.identifierhttp://dx.doi.org/10.1590/S0103-64402010000500013
dc.identifier.citationBrazilian Dental Journal, v. 21, n. 5, p. 452-457, 2010.
dc.identifier.doi10.1590/S0103-64402010000500013
dc.identifier.file2-s2.0-78650742051.pdf
dc.identifier.issn0103-6440
dc.identifier.issn1806-4760
dc.identifier.scieloS0103-64402010000500013
dc.identifier.scopus2-s2.0-78650742051
dc.identifier.urihttp://hdl.handle.net/11449/72083
dc.language.isoeng
dc.relation.ispartofBrazilian Dental Journal
dc.relation.ispartofsjr0,476
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectRoot resorption
dc.subjectTooth replantation
dc.subjectZoledronic acid
dc.subjectbisphosphonic acid derivative
dc.subjectbone density conservation agent
dc.subjectcalcium hydroxide
dc.subjectfluoride sodium
dc.subjectimidazole derivative
dc.subjectroot canal filling material
dc.subjectzoledronic acid
dc.subjectanimal
dc.subjectcementum
dc.subjectconnective tissue
dc.subjectdrug effect
dc.subjectendodontics
dc.subjectimage processing
dc.subjectmale
dc.subjectmethodology
dc.subjectrat
dc.subjecttime
dc.subjecttooth disease
dc.subjecttooth injury
dc.subjecttooth root
dc.subjecttooth socket
dc.subjectWistar rat
dc.subjectAnimals
dc.subjectBone Density Conservation Agents
dc.subjectCalcium Hydroxide
dc.subjectConnective Tissue
dc.subjectDental Cementum
dc.subjectDiphosphonates
dc.subjectImage Processing, Computer-Assisted
dc.subjectImidazoles
dc.subjectMale
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectRoot Canal Filling Materials
dc.subjectRoot Canal Obturation
dc.subjectRoot Canal Preparation
dc.subjectRoot Resorption
dc.subjectSodium Fluoride
dc.subjectTime Factors
dc.subjectTooth Ankylosis
dc.subjectTooth Avulsion
dc.subjectTooth Replantation
dc.subjectTooth Root
dc.subjectTooth Socket
dc.titleEffect of zoledronic acid used in the root surface treatment of late replanted teeth: A study in ratsen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/bdj/paboutj.htm
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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Artigos - Cirurgia e Clínica Integrada - FOA