Markers of uremia and pericardial effusion in peritoneal dialysis

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dc.contributor.authorAntunes, Aline de Araujo [UNESP]
dc.contributor.authorCaramori, Jacqueline Socorro Costa Teixeira [UNESP]
dc.contributor.authorVannini, Francieli Delatim [UNESP]
dc.contributor.authorZanati, Silmeia Garcia [UNESP]
dc.contributor.authorBarretti, Pasqual [UNESP]
dc.contributor.authorMatsubara, Beatriz Bojikian [UNESP]
dc.contributor.authorSilva Franco, Roberto Jorge da [UNESP]
dc.contributor.authorMartin, Luis Cuadrado [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:33:23Z
dc.date.available2014-05-20T13:33:23Z
dc.date.issued2012-06-01
dc.description.abstractInadequate dialysis causes accumulation of toxic residues that may lead to the development of dialysis-associated pericardial effusion, but several other factors could be associated with this abnormality. The purpose of this study was to evaluate clinical risk factors to asymptomatic pericardial effusion in peritoneal dialysis.This cross-sectional study included 34 patients aged a parts per thousand yen18 years on peritoneal dialysis for at least 3 months, who showed no symptomatic pericardial effusion, hepatic cirrhosis, neoplasias, lupus or amputations, none in minoxidil use. Asymptomatic pericardial effusion was diagnosed by echocardiography. Risk factors were evaluated by logistic regression and Roc curve. Significance level was set at P < 0.05.Patient age was 51 +/- A 15.9 years. of the 34 patients enrolled, 16 were men and 11 diabetic. Five of them presented pericardial effusion. Logistic regression identifies low hemoglobin level (RR 0.454 CI 95%: 0.225-0.913; P = 0.027), low phase angle (RR 0.236 CI 95%: 0.057-0.984; P = 0.048) and low Kt/V (RR 0.001 CI 95%: 0.0-0.492; P = 0.03) as risk factors to pericardial effusion. Roc curve showed that hemoglobin levels below 12.2 g/dL, Kt/V lower than 1.9 and phase angle lower than 4.5A degrees were the best cutoffs to predict pericardial effusion. Four patients showed these three parameters in the unfavorable range, and all these four patients presented pericardial effusion. The other patient with pericardial effusion had two of these parameters reduced.These findings corroborate the hypothesis that uremia plays a significant role in the pathogenesis of dialysis-associated pericardial effusion.en
dc.description.affiliationSão Paulo State Univ UNESP, Botucatu Med Sch, Dept Internal Med, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUnespSão Paulo State Univ UNESP, Botucatu Med Sch, Dept Internal Med, BR-18618970 Botucatu, SP, Brazil
dc.format.extent923-927
dc.identifierhttp://dx.doi.org/10.1007/s11255-011-0049-0
dc.identifier.citationInternational Urology and Nephrology. Dordrecht: Springer, v. 44, n. 3, p. 923-927, 2012.
dc.identifier.doi10.1007/s11255-011-0049-0
dc.identifier.issn0301-1623
dc.identifier.lattes5496411983893479
dc.identifier.lattes6990977122340795
dc.identifier.lattes7095933557855151
dc.identifier.lattes4923203168446615
dc.identifier.orcid0000-0003-4979-4836
dc.identifier.urihttp://hdl.handle.net/11449/11435
dc.identifier.wosWOS:000304402700033
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofInternational Urology and Nephrology
dc.relation.ispartofjcr1.692
dc.relation.ispartofsjr0,653
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectCardiovascularen
dc.subjectDialysisen
dc.subjectPericardial effusionen
dc.subjectPericarditisen
dc.subjectUremiaen
dc.titleMarkers of uremia and pericardial effusion in peritoneal dialysisen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-0-0-0
dcterms.rightsHolderSpringer
unesp.author.lattes5496411983893479[5]
unesp.author.lattes6990977122340795
unesp.author.lattes7095933557855151
unesp.author.lattes4923203168446615
unesp.author.orcid0000-0003-4979-4836[5]
unesp.author.orcid0000-0002-0607-8189[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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