Xylan from corn cobs, a promising polymer for drug delivery: Production and characterization

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dc.contributor.authorOliveira, Elquio Eleamen
dc.contributor.authorSilva, Acarilia Eduardo
dc.contributor.authorNagashima Junior, Toshiyuki
dc.contributor.authorSalgado Gomes, Monique Christine
dc.contributor.authorAguiar, Larissa Muratori
dc.contributor.authorMarcelino, Henrique Rodrigues
dc.contributor.authorAraujo, Ivonete Batista
dc.contributor.authorBayer, Marc P.
dc.contributor.authorRicardo, Nagila M. P. S.
dc.contributor.authorOliveira, Anselmo Gomes de [UNESP]
dc.contributor.authorTabosa Egito, Eryvaldo Socrates
dc.contributor.institutionUniversidade Federal do Rio Grande do Norte (UFRN)
dc.contributor.institutionUniv Estadual Paraiba
dc.contributor.institutionUniversidade Federal de Campina Grande (UFCG)
dc.contributor.institutionUniv Tubingen
dc.contributor.institutionUniversidade Federal do Ceará (UFC)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:24:49Z
dc.date.available2014-05-20T13:24:49Z
dc.date.issued2010-07-01
dc.description.abstractAlthough many authors have reported several beneficial effects ascribed to xylan, such as inhibitory action on mutagenicity activity. antiphlogistic effects, and mitogenic and comitogenic activities, few papers have investigated a systematic study on the technological properties of this polymer. The aim of the present work was to evaluate xylan as a promise raw material for the pharmaceutical industry. The water-insoluble xylan samples were extracted from corn cobs following several steps. The obtained powered sample was analyzed by infrared and RMN spectroscopy, and characterized regarding their particle size, bulk and tap densities, compressibility index, compactability, Hausner ratio, and angle of repose. According to the results, infrared and RMN spectroscopy were shown to be able to evaluate the xylan structural conformation and composition, respectively. In addition, rheological data demonstrated that xylan powder obtained from corn cobs may be characterized as a material with low density and very cohesive flow properties. (C) 2010 Elsevier Ltd. All rights reserved.en
dc.description.affiliationUniversidade Federal do Rio Grande do Norte (UFRN), PPGCSa, BR-59072970 Natal, RN, Brazil
dc.description.affiliationUniv Estadual Paraiba, CCBSA, Joao Pessoa, Paraiba, Brazil
dc.description.affiliationUniv Fed Campina Grande, UAS CES, Unidade Acad Saude, Cuite, PB, Brazil
dc.description.affiliationUniv Tubingen, Inst Organ Chem, D-72076 Tubingen, Germany
dc.description.affiliationUniversidade Federal do Ceará (UFC), Dept Quim Organ & Inorgan, Lab Polimeros, Fortaleza, Ceara, Brazil
dc.description.affiliationUNESP, Fac Ciencias Farmaceut, Dept Farmacos & Medicamentos, BR-14801902 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP, Fac Ciencias Farmaceut, Dept Farmacos & Medicamentos, BR-14801902 Araraquara, SP, Brazil
dc.description.sponsorshipBNB
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent5402-5406
dc.identifierhttp://dx.doi.org/10.1016/j.biortech.2010.01.137
dc.identifier.citationBioresource Technology. Oxford: Elsevier B.V., v. 101, n. 14, p. 5402-5406, 2010.
dc.identifier.doi10.1016/j.biortech.2010.01.137
dc.identifier.issn0960-8524
dc.identifier.lattes9114495952533044
dc.identifier.urihttp://hdl.handle.net/11449/7801
dc.identifier.wosWOS:000277581100047
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofBioresource Technology
dc.relation.ispartofjcr5.807
dc.relation.ispartofsjr2,029
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectXylanen
dc.subjectBiopolymeren
dc.subjectFourier transform infrareden
dc.subjectFlow propertiesen
dc.subjectBioresourceen
dc.titleXylan from corn cobs, a promising polymer for drug delivery: Production and characterizationen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.author.lattes9114495952533044[10]
unesp.author.orcid0000-0002-3625-7786[6]
unesp.author.orcid0000-0002-7214-4455[1]
unesp.author.orcid0000-0002-2180-3991[11]
unesp.author.orcid0000-0002-0107-9940[10]
unesp.author.orcid0000-0003-1849-5403[9]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

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Artigos - Fármacos e Medicamentos - FCFAR