Cardiorespiratory fitness, but not central obesity or C-reactive protein, is related to liver function in obese children

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dc.contributor.authorMartins, Clarice
dc.contributor.authorFreitas Jr., Ismael [UNESP]
dc.contributor.authorPizarro, Andréia
dc.contributor.authorAires, Luísa
dc.contributor.authorSilva, Gustavo
dc.contributor.authorSantos, Maria Paula
dc.contributor.authorMota, Jorge
dc.contributor.institutionHigh Education Institute from Maia
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionPorto University
dc.date.accessioned2014-05-27T11:28:42Z
dc.date.available2014-05-27T11:28:42Z
dc.date.issued2013-03-25
dc.description.abstractNonalcoholic fatty liver disease (NAFLD) is one of the most frequent complications associated with excess adiposity. Its pathogenesis is complex and there are multiple factors that may contribute to it. AIM: To analyze whether cardiorespiratory ftness (CRF), waist circumference (WC), and C-reactive protein (CRP) are associated with alanine aminotransferase (ALT) in children with obesity. METHODS: 79 overweight/obese children of both genders, 11-13 year-olds, with abnormal serum ALT from Porto public schools comprised the sample. Measurements included CRF (20-m Shuttle Run Test), WC (NHANES protocol), CRP and ALT (Cholestech LDX analyzer). Logistic regression adjusted for gender, maturation, and weight with ALT levels as dependent variable (risk vs. non risk), and WC (risk vs. non risk), CRP (risk vs. non risk), and CRF (fit vs. unfit) as independent variables. Level of significance was set at 95%. RESULTS: Logistic regression showed that obese fit children were less likely to have abnormal ALT values (OR=.031) CONCLUSION: In obese children, higher cardiovascular fitness appears to reduce the chance of decreased liver function. © 2013 Human Kinetics, Inc.en
dc.description.affiliationFaculty of Sports Research Centre in Physical Activity, Health and Leisure High Education Institute from Maia, Porto
dc.description.affiliationResearch Centre of Assessment and Exercise Prescription Univ. Estadual Paulista, São Paulo
dc.description.affiliationFaculty of Sports Research Centre in Physical Activity, Health and Leisure Porto University, Porto
dc.description.sponsorshipFoundation for Science and Technology
dc.format.extent3-11
dc.identifierhttp://journals.humankinetics.com/pes-back-issues/pes-volume-25-issue-1-february/cardiorespiratory-fitness-but-not-central-obesity-or-c-reactive-protein-is-related-to-liver-function-in-obese-children
dc.identifier.citationPediatric Exercise Science, v. 25, n. 1, p. 3-11, 2013.
dc.identifier.issn0899-8493
dc.identifier.issn1543-2920
dc.identifier.scopus2-s2.0-84875132489
dc.identifier.urihttp://hdl.handle.net/11449/74873
dc.identifier.wosWOS:000315842900002
dc.language.isoeng
dc.relation.ispartofPediatric Exercise Science
dc.relation.ispartofjcr1.353
dc.relation.ispartofsjr0,892
dc.relation.ispartofsjr0,892
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectalanine aminotransferase
dc.subjectC reactive protein
dc.subjectadolescent
dc.subjectblood
dc.subjectcardiovascular function
dc.subjectchild
dc.subjectexercise test
dc.subjectfemale
dc.subjectfitness
dc.subjecthuman
dc.subjectliver
dc.subjectmale
dc.subjectmetabolism
dc.subjectobesity
dc.subjectpathophysiology
dc.subjectphysiology
dc.subjectstatistical model
dc.subjectwaist circumference
dc.subjectAdolescent
dc.subjectAlanine Transaminase
dc.subjectC-Reactive Protein
dc.subjectCardiovascular Physiological Phenomena
dc.subjectChild
dc.subjectExercise Test
dc.subjectFemale
dc.subjectHumans
dc.subjectLiver
dc.subjectLogistic Models
dc.subjectMale
dc.subjectObesity
dc.subjectPhysical Fitness
dc.subjectWaist Circumference
dc.titleCardiorespiratory fitness, but not central obesity or C-reactive protein, is related to liver function in obese childrenen
dc.typeArtigo
dcterms.licensehttp://journals.humankinetics.com/terms-and-conditions-for-fair-use

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