Delayed tooth replantation in rats: effect of systemic antibiotic therapy with amoxicillin and tetracycline

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dc.contributor.authorGomes, Weglis Dyanne de Souza [UNESP]
dc.contributor.authorSilva, Cristina Antoniali [UNESP]
dc.contributor.authorMelo, Moriel Evangelista [UNESP]
dc.contributor.authorSilva, Vanessa Ferreira da [UNESP]
dc.contributor.authorAlmeida, Melyna Marques de [UNESP]
dc.contributor.authorPedrini, Denise [UNESP]
dc.contributor.authorPoi, Wilson Roberto [UNESP]
dc.contributor.authorSonoda, Celso Koogi [UNESP]
dc.contributor.authorPanzarini, Sônia Regina [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2015-12-07T15:37:17Z
dc.date.available2015-12-07T15:37:17Z
dc.date.issued2015-08-31
dc.description.abstractSystemic antibiotic therapy (SAT) has usually been recommended after tooth replantation, but its actual value has been questioned. As there are no reports in the literature about its influence on tooth replantation, the aim of this study was to evaluate the influence of systemic administration of antibiotics (amoxicillin and tetracycline) at the different phases of the repair process (7, 15, 30 days) in delayed rat tooth replantation. Ninety Wistar rats (Rattus norvegicus albinus) had their maxillary right incisors extracted and bench-dried for 60 min. The dental papilla, enamel organ, pulp tissue, and root surface-adhered periodontal ligament were removed, and the teeth were replanted. The animals received no antibiotics (n = 30) or were medicated systemically with amoxicillin (n = 30) and tetracycline (n = 30), and were euthanized after 7, 15, and 30 days. Regardless of the evaluation period, the acute inflammatory infiltrate was less intense and root resorption presented smaller extent and depth in the group treated with amoxicillin. The results suggest that SAT has a positive influence on the repair process in delayed tooth replantation and that amoxicillin is an excellent treatment option.en
dc.description.affiliationDepartment of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP - Univ Estadual Paulista, Araçatuba, SP, Brazil.
dc.description.affiliationUnespDepartment of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP - Univ Estadual Paulista, Araçatuba, SP, Brazil.
dc.format.extent448-456
dc.identifierhttp://dx.doi.org/10.1111/edt.12207
dc.identifier.citationDental Traumatology : Official Publication Of International Association For Dental Traumatology, 2015.
dc.identifier.doi10.1111/edt.12207
dc.identifier.issn1600-9657
dc.identifier.lattes6656433539493879
dc.identifier.lattes4185776888167996
dc.identifier.lattes5007703439443544
dc.identifier.pubmed26332890
dc.identifier.urihttp://hdl.handle.net/11449/131543
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofDental Traumatology : Official Publication Of International Association For Dental Traumatology
dc.relation.ispartofsjr0,724
dc.rights.accessRightsAcesso restrito
dc.sourcePubMed
dc.subjectAmoxicillinen
dc.subjectDelayed tooth replantationen
dc.subjectRoot resorptionen
dc.subjectTetracyclineen
dc.titleDelayed tooth replantation in rats: effect of systemic antibiotic therapy with amoxicillin and tetracyclineen
dc.typeArtigo
dcterms.rightsHolderWiley-Blackwell
unesp.author.lattes6656433539493879
unesp.author.lattes4185776888167996
unesp.author.lattes5007703439443544
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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Artigos - Cirurgia e Clínica Integrada - FOA