The effect of conventional mechanical periodontal treatment on red complex microorganisms and clinical parameters in Down syndrome periodontitis patients: a pilot study

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dc.contributor.authorTanaka, Marcia Hiromi [UNESP]
dc.contributor.authorRodrigues, Thamiris Orrico [UNESP]
dc.contributor.authorFinoti, L. S. [UNESP]
dc.contributor.authorTeixeira, S. R. L.
dc.contributor.authorMayer, M. P. A.
dc.contributor.authorScarel-Caminaga, Raquel Mantuaneli [UNESP]
dc.contributor.authorGiro, Elisa Maria Aparecida [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2015-08-06T16:14:04Z
dc.date.available2015-08-06T16:14:04Z
dc.date.issued2014
dc.description.abstractPeriodontal disease (PD) is induced by a complex microbiota, such as Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola (together called the red complex), which triggers intense inflammatory reaction. Down syndrome (DS) individuals demonstrate a high prevalence of PD compared with those who are otherwise chromosomally normal (euploids). This pilot study aimed to evaluate the effect of non-surgical periodontal treatment in DS chronic periodontitis patients on clinical and microbiological parameters. Patients with chronic periodontitis, 23 DS and 12 euploids (control group), were submitted to non-surgical mechanical periodontal treatment, followed by maintenance for 45 days. Clinical parameters after periodontal treatment were similar in diseased and healthy sites, independent of the genetic background. Diseased sites of DS and control patients harbored similar levels of P. gingivalis and T. forsythia at baseline, but significantly higher levels of T. denticola were found in DS patients. Increased levels of P. gingivalis at healthy sites were found in DS individuals. Non-surgical periodontal therapy decreased the levels of red complex microorganisms and improved the tested clinical parameters of diseased sites in both groups. However, the levels of red complex bacteria were higher in diseased sites of DS patients after the periodontal treatment. We conclude in this pilot study that, although the mechanical periodontal treatment seemed to be effective in DS subjects over a short-term period, the red complex bacteria levels did not decrease significantly in diseased sites, as occurred in controls. Therefore, for DS patients, it seems that the conventional non-surgical periodontal therapy should be improved by utilizing adjuvants to reduce the presence of periodontopathogens.en
dc.description.affiliationDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá, 1680, Centro, CEP 14801903, SP, Brasil
dc.description.affiliationUnespDepartment of Orthodontics and Pediatric Dentistry
dc.description.affiliationUnespDepartment of Morphology
dc.format.extent601-608
dc.identifierhttp://link.springer.com/article/10.1007%2Fs10096-014-2268-7
dc.identifier.citationEuropean Journal of Clinical Microbiology & Infectious Diseases, v. 34, n. 3, p. 601-608, 2014.
dc.identifier.doi10.1007/s10096-014-2268-7
dc.identifier.issn0934-9723
dc.identifier.lattes0097031682063652
dc.identifier.lattes6623534840976883
dc.identifier.urihttp://hdl.handle.net/11449/126143
dc.language.isoeng
dc.relation.ispartofEuropean Journal of Clinical Microbiology & Infectious Diseases
dc.relation.ispartofjcr2.537
dc.relation.ispartofsjr1,312
dc.rights.accessRightsAcesso restrito
dc.sourceCurrículo Lattes
dc.titleThe effect of conventional mechanical periodontal treatment on red complex microorganisms and clinical parameters in Down syndrome periodontitis patients: a pilot studyen
dc.typeArtigo
unesp.author.lattes0097031682063652
unesp.author.lattes6623534840976883
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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