Vaginal Flora Alterations and Clinical Symptoms in Low-Risk Pregnant Women

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dc.contributor.authorGondo, Fausto [UNESP]
dc.contributor.authorSilva, Marcia da [UNESP]
dc.contributor.authorPolettini, Jossimara [UNESP]
dc.contributor.authorTristao, Andrea da R. [UNESP]
dc.contributor.authorPeraçoli, José Carlos [UNESP]
dc.contributor.authorWitkin, Steven Sol [UNESP]
dc.contributor.authorRudge, Marilza Vieira Cunha [UNESP]
dc.contributor.institutionCornell Univ
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:35:21Z
dc.date.available2014-05-20T13:35:21Z
dc.date.issued2011-01-01
dc.description.abstractBackground: To evaluate associations between alterations in vaginal flora and clinical symptoms in low-risk pregnant women. Methods: Vaginal specimens from 245 pregnant women were analyzed by microscopy for vaginal flora. Signs and symptoms of vaginal infection were determined by patient interviews and gynecologic examinations. Results: Abnormal vaginal flora was identified in 45.7% of the subjects. The final clinical diagnoses were bacterial vaginosis (21.6%), vaginal candidosis (10.2%), intermediate vaginal flora (5.2%), aerobic vaginitis (2.9%), mixed flora (2.9%) and other abnormal findings (2.9%). The percentage of women with or without clinical signs or symptoms was not significantly different between these categories. The presence of vaginal odor or vaginal discharge characteristics was not diagnostic of any specific flora alteration; pruritus was highly associated with candidosis (p < 0.0001). Compared to women with normal flora, pruritus was more prevalent in women with candidosis (p < 0.0001), while vaginal odor was associated with bacterial vaginosis (p = 0.0026). Conclusion: The prevalence of atypical vaginal flora is common in our low-risk pregnant population and is not always associated with pathology. The occurrence of specific signs or symptoms does not always discriminate between women with different types of atypical vaginal flora or between those with abnormal and normal vaginal flora. Copyright (C) 2010 S. Karger AG, Baselen
dc.description.affiliationCornell Univ, Weill Med Coll, Dept Obstet & Gynecol, New York, NY 10065 USA
dc.description.affiliationUNESP São Paulo State Univ, Botucatu Med Sch, Dept Gynecol & Obstet, Botucatu, SP, Brazil
dc.description.affiliationUNESP São Paulo State Univ, Botucatu Med Sch, Dept Pathol, Botucatu, SP, Brazil
dc.description.affiliationUnespUNESP São Paulo State Univ, Botucatu Med Sch, Dept Gynecol & Obstet, Botucatu, SP, Brazil
dc.description.affiliationUnespUNESP São Paulo State Univ, Botucatu Med Sch, Dept Pathol, Botucatu, SP, Brazil
dc.format.extent158-162
dc.identifierhttp://dx.doi.org/10.1159/000316051
dc.identifier.citationGynecologic and Obstetric Investigation. Basel: Karger, v. 71, n. 3, p. 158-162, 2011.
dc.identifier.doi10.1159/000316051
dc.identifier.issn0378-7346
dc.identifier.lattes8499437381595614
dc.identifier.lattes6758680388835078
dc.identifier.orcid0000-0002-9227-832X
dc.identifier.urihttp://hdl.handle.net/11449/12152
dc.identifier.wosWOS:000289890400003
dc.language.isoeng
dc.publisherKarger
dc.relation.ispartofGynecologic and Obstetric Investigation
dc.relation.ispartofjcr1.183
dc.relation.ispartofsjr0,545
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectVaginal floraen
dc.subjectBacterial vaginosisen
dc.subjectCandidosisen
dc.subjectAerobic vaginitisen
dc.subjectVaginal symptomsen
dc.subjectPregnancyen
dc.titleVaginal Flora Alterations and Clinical Symptoms in Low-Risk Pregnant Womenen
dc.typeArtigo
dcterms.licensehttp://www.karger.com/Journal/Guidelines/238704#15
dcterms.rightsHolderKarger
unesp.author.lattes8499437381595614
unesp.author.lattes6758680388835078
unesp.author.orcid0000-0002-6719-8715[3]
unesp.author.orcid0000-0002-9227-832X[7]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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