Gingival primary extranodal non-Hodgkin's lymphoma as the first manifestation of acquired immunodeficiency syndrome

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dc.contributor.authorNavarro, Cláudia Maria [UNESP]
dc.contributor.authorShibli, Jamil A.
dc.contributor.authorFerrari, Roberto B.
dc.contributor.authord'Avila, Susana
dc.contributor.authorSposto, Maria R. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Guarulhos
dc.date.accessioned2013-09-30T18:31:41Z
dc.date.accessioned2014-05-20T13:45:19Z
dc.date.available2013-09-30T18:31:41Z
dc.date.available2014-05-20T13:45:19Z
dc.date.issued2008-03-01
dc.description.abstractBackground: Non-Hodgkin's lymphomas (NHLs) are a heterogeneous group of lymphoproliferative malignancies that may be associated with acquired immunodeficiency syndrome (AIDS). NHL can disseminate to extranodal sites; however, its dissemination to the jaws and mouth is not common. This report presents and discusses two unusual cases of gingival primary extranodal non-Hodgkin's lymphoma (PE-NHL) as the first manifestation of AIDS.Methods: Two mates presented with asymptomatic gingival swelling. They were examined clinically. Biopsies of the gingival tissue were evaluated using routine histologic techniques and immunohistochemistry. The patients were tested for human immunodeficiency virus (HIV) infection.Results: The clinicopathological evaluation and the serological HIV examination of the patients led us to the final diagnosis of gingival PE-NHL as the first manifestation of AIDS. Both patients were referred to an oncologist and to an infectious disease specialist and were given antineoplastic chemotherapy and highly active antiretroviral therapy. Only one patient presented a favorable clinical evolution.Conclusion: The present case reports have important clinical implications; the two unusual presentations of gingival PE-NHL contribute to information about the differential diagnosis of rapidly progressing gingival swelling.en
dc.description.affiliationSão Paulo State Univ, Araraquara Dent Sch, Dept Oral Diag & Surg, BR-14801903 Araraquara, SP, Brazil
dc.description.affiliationUniv Guarulhos, Dent Res Div, Dept Periodontol, Guarulhos, SP, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Araraquara Dent Sch, Dept Oral Diag & Surg, BR-14801903 Araraquara, SP, Brazil
dc.format.extent562-566
dc.identifierhttp://dx.doi.org/10.1902/jop.2008.070229
dc.identifier.citationJournal of Periodontology. Chicago: Amer Acad Periodontology, v. 79, n. 3, p. 562-566, 2008.
dc.identifier.doi10.1902/jop.2008.070229
dc.identifier.issn0022-3492
dc.identifier.lattes7650237459252010
dc.identifier.orcid0000-0002-3185-2826
dc.identifier.urihttp://hdl.handle.net/11449/15935
dc.identifier.wosWOS:000253923700023
dc.language.isoeng
dc.publisherAmer Acad Periodontology
dc.relation.ispartofJournal of Periodontology
dc.relation.ispartofjcr3.392
dc.relation.ispartofsjr1,408
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectAIDSen
dc.subjectcase reporten
dc.subjectgingivaen
dc.subjectHIVen
dc.subjectnon-Hodgkin'sen
dc.subjectlymphomaen
dc.titleGingival primary extranodal non-Hodgkin's lymphoma as the first manifestation of acquired immunodeficiency syndromeen
dc.typeArtigo
dcterms.licensehttp://www.joponline.org/page/permissionRequests.jsp
dcterms.rightsHolderAmer Acad Periodontology
unesp.author.lattes7650237459252010[1]
unesp.author.orcid0000-0003-1971-0195[2]
unesp.author.orcid0000-0002-3185-2826[1]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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