A importância do teste de tolerância à glicose oral no diagnóstico da intolerância à glicose e diabetes mellitus do tipo 2 em mulheres com síndrome dos ovários policísticos

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dc.contributor.authorSantos, Ana Gabriela Pontes [UNESP]
dc.contributor.authorRehme, Marta Francis Benevides [UNESP]
dc.contributor.authorMicussi, Maria Thereza Albuquerque Barbosa Cabral [UNESP]
dc.contributor.authorde Oliveira Maranhão, Técia Maria [UNESP]
dc.contributor.authorde Paula Pimenta, Walkyria [UNESP]
dc.contributor.authorde Carvalho, Lídia Raquel [UNESP]
dc.contributor.authorPontes, Anaglória [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Paraná (UFPR)
dc.contributor.institutionUniversidade Federal do Rio Grande do Norte (UFRN)
dc.date.accessioned2014-05-27T11:26:24Z
dc.date.available2014-05-27T11:26:24Z
dc.date.issued2012-03-01
dc.description.abstractPURPOSE: To evaluate the importance of the oral glucose tolerance test for the diagnosis of glucose intolerance (GI) and type 2 diabetes mellitus (DM-2) in women with PCOS. METHODS: A retrospective study was conducted on 247 patients with PCOS selected at random. The diagnosis of GI was obtained from the two-hour oral glucose tolerance test with 75 g of glucose according to the criteria of the World Health Organization (WHO) (GI: 120 minutes for plasma glucose =140 mg/dL and <200 mg/dL), and the diagnosis of DM-2 was obtained by both the oral glucose tolerance test (DM: 120 minutes for plasma glucose =200 mg/dL) and fasting glucose using the criteria of the American Diabetes Association (impaired fasting glucose: fasting plasma glucose =100 and <126 mg/dL; DM: fasting glucose =126 mg/dL). A logistic regression model for repeated measures was applied to compare the oral glucose tolerance test with fasting plasma glucose. ANOVA followed by the Tukey test was used for the analysis of the clinical and biochemical characteristics of patients with and without GI and/or DM-2. A p<0.05 was considered statistically significant. RESULTS: PCOS patients had a mean age of 24.8±6.3, and body mass index (BMI) of 18.3 to 54.9 kg/m2 (32.5±7.6). The percentage of obese patients was 64%, the percentage of overweight patients was 18.6% and 17.4% had healthy weight. The oral glucose tolerance test identified 14 cases of DM-2 (5.7%), while fasting glucose detected only three cases (1.2%), and the frequency of these disorders was higher with increasing age and BMI. CONCLUSIONS: The results of this study demonstrate the superiority of the oral glucose tolerance test in relation to fasting glucose in diagnosing DM-2 in young women with PCOS and should be performed in these patients.en
dc.description.affiliationPrograma de Pós-graduação em Ginecologia, Obstetrícia e Mastologia Faculdade de Medicina, Botucatu da Universidade Estadual Paulista Julio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationDepartamento de Tocoginecologia Universidade Federal do Paraná UFPR, Curitiba (PR)
dc.description.affiliationDepartamento de Fisioterapia Universidade Federal do Rio Grande do Norte UFRN, Natal (RN)
dc.description.affiliationDepartamento de Tocoginecologia e Programa, Pos-graduaao em Ciencias da Saude Universidade Federal do Rio Grande do Norte UFRN, Natal (RN)
dc.description.affiliationDepartamento de Clínica Médica, Faculdade de Medicina de Botucatu Universidade Estadual Paulista Julio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationDepartamento de Bioestatística, Instituto de Biociências Universidade Estadual Paulista Júlio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationObstetricia e Mastologia, Departamento de Ginecologia e Obstetricia Universidade Estadual Paulista Julio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationTrabalho realizado no Departamento de Ginecologia e Obstetricia, Faculdade de Medicina de Botucatu Universidade Estadual Paulista Júlio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationUnespPrograma de Pós-graduação em Ginecologia, Obstetrícia e Mastologia Faculdade de Medicina, Botucatu da Universidade Estadual Paulista Julio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationUnespDepartamento de Clínica Médica, Faculdade de Medicina de Botucatu Universidade Estadual Paulista Julio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationUnespDepartamento de Bioestatística, Instituto de Biociências Universidade Estadual Paulista Júlio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationUnespObstetricia e Mastologia, Departamento de Ginecologia e Obstetricia Universidade Estadual Paulista Julio de Mesquita Filho UNESP, Botucatu (SP)
dc.description.affiliationUnespTrabalho realizado no Departamento de Ginecologia e Obstetricia, Faculdade de Medicina de Botucatu Universidade Estadual Paulista Júlio de Mesquita Filho UNESP, Botucatu (SP)
dc.format.extent128-132
dc.identifierhttp://dx.doi.org/10.1590/S0100-72032012000300007
dc.identifier.citationRevista Brasileira de Ginecologia e Obstetricia, v. 34, n. 3, p. 128-132, 2012.
dc.identifier.doi10.1590/S0100-72032012000300007
dc.identifier.file2-s2.0-84859587854.pdf
dc.identifier.issn0100-7203
dc.identifier.lattes0514178654667684
dc.identifier.lattes6507858203899415
dc.identifier.lattes0514178654667684
dc.identifier.lattes0514178654667684
dc.identifier.lattes6507858203899415
dc.identifier.scieloS0100-72032012000300007
dc.identifier.scopus2-s2.0-84859587854
dc.identifier.urihttp://hdl.handle.net/11449/73213
dc.language.isoeng
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Ginecologia e Obstetrícia
dc.relation.ispartofsjr0,292
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectDiabetes mellitus
dc.subjectGlucose intolerance/diagnosis
dc.subjectObesity
dc.subjectPolycystic ovary syndrome
dc.subjectadult
dc.subjectfemale
dc.subjectglucose intolerance
dc.subjectglucose tolerance test
dc.subjecthuman
dc.subjectnon insulin dependent diabetes mellitus
dc.subjectovary polycystic disease
dc.subjectretrospective study
dc.subjectAdult
dc.subjectDiabetes Mellitus, Type 2
dc.subjectFemale
dc.subjectGlucose Intolerance
dc.subjectGlucose Tolerance Test
dc.subjectHumans
dc.subjectPolycystic Ovary Syndrome
dc.subjectRetrospective Studies
dc.subjectYoung Adult
dc.titleA importância do teste de tolerância à glicose oral no diagnóstico da intolerância à glicose e diabetes mellitus do tipo 2 em mulheres com síndrome dos ovários policísticospt
dc.title.alternativeThe importance of oral glucose tolerance test in diagnosis of glucose intolerance and type 2 diabetes mellitus in women with polycystic ovary syndromeen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rbgo/paboutj.htm#3
unesp.author.lattes0514178654667684
unesp.author.lattes0514178654667684
unesp.author.lattes6507858203899415
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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