Symptom dimensions, clinical course and comorbidity in men and women with obsessive-compulsive disorder

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dc.contributor.authorTorresan, Ricardo C. [UNESP]
dc.contributor.authorRamos-Cerqueira, Ana Teresa A. [UNESP]
dc.contributor.authorShavitt, Roseli G.
dc.contributor.authordo Rosário, Maria Conceição
dc.contributor.authorde Mathis, Maria Alice
dc.contributor.authorMiguel, Euripedes C.
dc.contributor.authorTorres, Albina Rodrigues [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:30:45Z
dc.date.available2014-05-27T11:30:45Z
dc.date.issued2013-09-30
dc.description.abstractThe study aimed to compare male and female patients with obsessive-compulsive disorder (OCD) across symptom dimensions, clinical course and comorbidity. A cross-sectional study was undertaken with 858 adult OCD patients (DSM-IV) from the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders. Patients were evaluated using structured interviews, including the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) and the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I). The sample was composed of 504 women (58.7%) and 354 men (41.3%) with a mean age of 35.4 years-old (range: 18-77). Men were younger, more frequently single and presented more tics, social phobia and alcohol use disorders. Among men, symptom interference occurred earlier and symptoms of the sexual/religious dimension were more common and more severe. Conversely, women were more likely to present symptoms of the aggressive, contamination/cleaning and hoarding dimension and comorbidity with specific phobias, anorexia nervosa, bulimia, trichotillomania, skin picking and compulsive buying. In the logistic regression, female gender remained independently associated with the aggressive and contamination/cleaning dimensions. In both genders the aggressive dimension remained associated with comorbid post-traumatic stress disorder, the sexual/religious dimension with major depression and the hoarding dimension with tic disorders. Gender seems to be relevant in the determination of OCD clinical presentation and course and should be considered an important aspect when defining more homogeneous OCD subgroups. © 2012 Elsevier B.V.en
dc.description.affiliationDepartment of Neurology, Psychology and Psychiatry Botucatu Medical School Univ Estadual Paulista (UNESP), Botucatu, SP
dc.description.affiliationDepartment and Institute of Psychiatry São Paulo University Medical School (USP), São Paulo (SP)
dc.description.affiliationChild and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry and Psychology Federal University of São Paulo (UNIFESP), São Paulo (SP)
dc.description.affiliationUnespDepartment of Neurology, Psychology and Psychiatry Botucatu Medical School Univ Estadual Paulista (UNESP), Botucatu, SP
dc.format.extent186-195
dc.identifierhttp://dx.doi.org/10.1016/j.psychres.2012.12.006
dc.identifier.citationPsychiatry Research, v. 209, n. 2, p. 186-195, 2013.
dc.identifier.doi10.1016/j.psychres.2012.12.006
dc.identifier.issn0165-1781
dc.identifier.issn1872-7123
dc.identifier.lattes3837157956819433
dc.identifier.scopus2-s2.0-84883228626
dc.identifier.urihttp://hdl.handle.net/11449/76664
dc.identifier.wosWOS:000324791500010
dc.language.isoeng
dc.relation.ispartofPsychiatry Research
dc.relation.ispartofjcr2.223
dc.relation.ispartofsjr1,215
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectGender
dc.subjectObsessive-compulsive disorder
dc.subjectPhenomenology
dc.subjectPhenotype
dc.subjectSex
dc.subjectSymptom dimensions
dc.subjectadult
dc.subjectaged
dc.subjectaggression
dc.subjectalcohol use disorder
dc.subjectanorexia nervosa
dc.subjectBrazil
dc.subjectbulimia
dc.subjectcleaning
dc.subjectcomorbidity
dc.subjectcompulsion
dc.subjectcontrolled study
dc.subjectcross-sectional study
dc.subjectdisease course
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmajor depression
dc.subjectmale
dc.subjectobsessive compulsive disorder
dc.subjectobsessive hoarding
dc.subjectposttraumatic stress disorder
dc.subjectprevalence
dc.subjectpriority journal
dc.subjectreligion
dc.subjectsex difference
dc.subjectsexual function
dc.subjectsocial phobia
dc.subjectStructured Clinical Interview for DSM Disorders
dc.subjectsymptom
dc.subjecttic
dc.subjecttrichotillomania
dc.subjectYale Brown Obsessive Compulsive Scale
dc.titleSymptom dimensions, clinical course and comorbidity in men and women with obsessive-compulsive disorderen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
unesp.author.lattes3837157956819433[7]
unesp.author.lattes0537835246490556[2]
unesp.author.orcid0000-0003-1072-5008[7]
unesp.author.orcid0000-0003-2374-8890[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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