Topical use of fluorides for caries control

dc.contributor.authorPessan, Juliano Pelim [UNESP]
dc.contributor.authorToumba, Kyriacos Jack
dc.contributor.authorBuzalaf, Marília Afonso Rabelo
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversity of Leeds
dc.date.accessioned2014-05-27T11:25:54Z
dc.date.available2014-05-27T11:25:54Z
dc.date.issued2011-06-01
dc.description.abstractSince the early findings on the protective effects of fluoride present in drinking water upon caries incidence and prevalence, intensive research has been conducted in order to determine the benefits, safety, as well as the cost-effectiveness of other modalities of fluoride delivery. The present chapter reviews the various forms of topical fluoride use - professionally and self-applied - with special emphasis on clinical efficacy and possible side effects. The most widely used forms of fluoride delivery have been subject of several systematic reviews, providing strong evidence supporting the use of dentifrices, gels, varnishes and mouth rinses for the control of caries progression. Dentifrices with fluoride concentrations of 1,000 ppm and above have been shown to be clinically effective in caries prevention when compared to a placebo treatment, but the evidence regarding formulations with 450-550 ppm is still subject of debate. Therefore, the recommendation for low-fluoride dentifrice use must take into account both risks and benefits. The evidence for the combined use of two modalities of fluoride application in comparison to a single modality is still inconsistent, implying that more studies with adequate methodology are needed to determine the real benefits of each method. Considering the currently available evidence and risk-benefit aspects, it seems justifiable to recommend the use of fluoridated dentifrices to individuals of all ages, and additional fluoride therapy should also be targeted towards individuals at high caries risk. © 2011 S. Karger AG, Basel.en
dc.description.affiliationDepartment of Pediatric Dentistry and Public Health Araçatuba Dental School São Paulo State University, Rua José Bonifácio, 1193, 16015-050 Araçatuba - SP
dc.description.affiliationDepartment of Biological Sciences Bauru Dental School University of São Paulo, Bauru
dc.description.affiliationDivision of Child Dental Health Leeds Dental Institute University of Leeds, Leeds
dc.description.affiliationUnespDepartment of Pediatric Dentistry and Public Health Araçatuba Dental School São Paulo State University, Rua José Bonifácio, 1193, 16015-050 Araçatuba - SP
dc.format.extent115-132
dc.identifierhttp://dx.doi.org/10.1159/000325154
dc.identifier.citationMonographs in Oral Science, v. 22, p. 115-132.
dc.identifier.doi10.1159/000325154
dc.identifier.issn0077-0892
dc.identifier.issn1662-3843
dc.identifier.scopus2-s2.0-79960256953
dc.identifier.urihttp://hdl.handle.net/11449/72469
dc.language.isoeng
dc.relation.ispartofMonographs in Oral Science
dc.relation.ispartofsjr2,017
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectanticaries agent
dc.subjectfluoride
dc.subjectfluoride varnish
dc.subjectmouthwash
dc.subjecttoothpaste
dc.subjectchemistry
dc.subjectdental caries
dc.subjectdisease course
dc.subjecthuman
dc.subjectreview
dc.subjectrisk assessment
dc.subjectCariostatic Agents
dc.subjectChemistry, Pharmaceutical
dc.subjectDental Caries
dc.subjectDental Caries Susceptibility
dc.subjectDentifrices
dc.subjectDisease Progression
dc.subjectFluorides
dc.subjectFluorides, Topical
dc.subjectHumans
dc.subjectMouthwashes
dc.subjectRisk Assessment
dc.titleTopical use of fluorides for caries controlen
dc.typeArtigo
dcterms.licensehttp://www.karger.com/Services/RightsPermissions
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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