Ventilator-induced lung injury and acute respiratory distress syndrome: a basic science review

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dc.contributor.authorRonchi, Carlos Fernando [UNESP]
dc.contributor.authorKlefens, Susiane de Oliveira [UNESP]
dc.contributor.authorFerreira, Ana Lúcia dos Anjos [UNESP]
dc.contributor.authorRonchi, Carolina Bragiola Berchieri [UNESP]
dc.contributor.authorCarpi, Mário Ferreira [UNESP]
dc.contributor.authorMoraes, Marcos Aurélio [UNESP]
dc.contributor.authorKurokawa, Cilmery Suemi [UNESP]
dc.contributor.authorGimenes, Camila
dc.contributor.authorArca, Eduardo Aguilar
dc.contributor.authorFioretto, José Roberto [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade do Sagrado Coração (USC)
dc.date.accessioned2016-04-01T18:43:39Z
dc.date.available2016-04-01T18:43:39Z
dc.date.issued2012
dc.description.abstractAcute respiratory distress syndrome is the most severe manifestation of acute lung injury and it is associated with high mortality rate. Despite better understanding of ARDS pathophysiology, its mechanism is still unclear. Mechanical ventilation is the main ARDS supportive treatment. However, mechanical ventilation is a non-physiologic process and complications are associated with its application. Mechanical ventilation may induce lung injury, referred to as ventilator-induced lung injury. Frequently, VILI is related to macroscopic injuries associated with alveolar rupture. The present article is a review of the literature on ventilator-induced lung injury in acute respiratory distress syndrome. Animal and human studies were reviewed. We mainly selected publications in the past 5 years, but did not exclude commonly referenced and highly regarded older publications.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Pediatria, Botucatu, SP, Brasil
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Clínica Médica, Botucatu, SP, Brasil
dc.description.affiliationUniversidade do Sagrado Coração (USC), Bauru, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Pediatria, Botucatu, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Clínica Médica, Botucatu, SP, Brasil
dc.format.extent1-6
dc.identifierhttp://dx.doi.org/10.4172/2161-105X.S12-001
dc.identifier.citationJournal of Pulmonary and Respiratory Medicine, v. S12, n. 001, p. 1-6, 2012.
dc.identifier.doi10.4172/2161-105X.S12-001
dc.identifier.fileISSN2161-105X-2012-S12-001-01-06.pdf
dc.identifier.issn2161-105X
dc.identifier.lattes2940051650846541
dc.identifier.lattes8510423269540465
dc.identifier.orcid0000-0003-1380-7527
dc.identifier.urihttp://hdl.handle.net/11449/136986
dc.language.isoeng
dc.relation.ispartofJournal of Pulmonary and Respiratory Medicine
dc.rights.accessRightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectVentilator-induced lung injuryen
dc.subjectMechanical ventilationen
dc.subjectAcute lung injuryen
dc.subjectAcute respiratory distress syndromeen
dc.titleVentilator-induced lung injury and acute respiratory distress syndrome: a basic science reviewen
dc.typeArtigo
unesp.author.lattes2940051650846541[3]
unesp.author.lattes8510423269540465[7]
unesp.author.orcid0000-0002-5267-1127[3]
unesp.author.orcid0000-0003-1380-7527[7]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentPediatriapt
unesp.departmentClínica Médicapt

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