Histological analysis of effects of 24% EDTA gel for nonsurgical treatment of periodontal tissues

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dc.contributor.authorVasconcellos, Luana Marotta Reis de [UNESP]
dc.contributor.authorRicardo, Lucilene Hernandes
dc.contributor.authorBalducci, Ivan [UNESP]
dc.contributor.authorVasconcellos, Luis Gustavo Oliveira de
dc.contributor.authorCarvalho, Yasmin Rodarte [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de Taubaté (UNITAU)
dc.date.accessioned2015-12-07T15:29:52Z
dc.date.available2015-12-07T15:29:52Z
dc.date.issued2006
dc.description.abstractThe aim of this study was to investigate, by means of histological and histomorphometric analysis, the effects of 24% ethylenediaminetetraacetic acid (EDTA) gel in periodontal tissue when used in combination with conventional periodontal treatment. Periodontitis was induced in the 2nd upper left permanent molars of 45 male Wistar rats by means of ligature. After 5 weeks, this was removed and debridement was performed. The animals were then randomly divided into 3 groups; group 1: mechanical treatment, group 2: mechanical treatment and EDTA gel application for 2 min, and group 3: mechanical treatment and placebo gel application for 2 min. After the treatment, rinsing was done with 0.9% saline solution for 1 min in all cases, followed by root notching in the deepest part of the pocket. After 4, 10, and 28 days the animals were sacrificed. The averages obtained were evaluated by means of test two-way analysis of variance (ANOVA) and Tukey statistical tests (P < 0.05). The results showed that with respect to the type of treatment employed, there were no statistically significant differences in the vitality of the periodontal tissue. It was concluded that 24% EDTA gel did not interfere with periodontal tissue repair when used in combination with conventional periodontal treatment.en
dc.description.affiliationDepartment of Bioscience and Buccal Diagnosis, Dental School of São José dos Campos, State University of Sao Paulo, São José dos Campos, Brazil.
dc.description.affiliationUnespDepartment of Bioscience and Buccal Diagnosis, Dental School of São José dos Campos, State University of Sao Paulo, São José dos Campos, Brazil.
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent207-214
dc.identifierhttp://doi.org/10.2334/josnusd.48.207
dc.identifier.citationJournal Of Oral Science, v. 48, n. 4, p. 207-214, 2006.
dc.identifier.doi10.2334/josnusd.48.207
dc.identifier.issn1343-4934
dc.identifier.lattes6967369119792151
dc.identifier.lattes5006685136114327
dc.identifier.pubmed17220618
dc.identifier.urihttp://hdl.handle.net/11449/130868
dc.language.isoeng
dc.publisherNihon University School of Dentistry
dc.relation.ispartofJournal Of Oral Science
dc.relation.ispartofjcr0.853
dc.relation.ispartofsjr0,397
dc.rights.accessRightsAcesso restrito
dc.sourcePubMed
dc.titleHistological analysis of effects of 24% EDTA gel for nonsurgical treatment of periodontal tissuesen
dc.typeArtigo
dcterms.rightsHolderNihon University School of Dentistry
unesp.author.lattes6967369119792151
unesp.author.lattes5006685136114327
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia, São José dos Campospt

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