Use of salivary biomarkers for diagnosis of periodontal disease activity: a literature review

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dc.contributor.authorRocha, Fernanda Regina Godoy [UNESP]
dc.contributor.authorMolon, Rafael Scaf de [UNESP]
dc.contributor.authorTonetto, Mateus Rodrigues [UNESP]
dc.contributor.authorPinto, Shelon Cristina Souza
dc.contributor.authorMuñoz, Eduardo Mariscal [UNESP]
dc.contributor.authorSampaio, Jose Eduardo Cezar [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de Ponta Grossa
dc.date.accessioned2015-08-06T16:12:39Z
dc.date.available2015-08-06T16:12:39Z
dc.date.issued2013
dc.description.abstractPeriodontal disease is an infectious disease characterized by the connective tissue destruction and consequent alveolar bone loss in response to plaque accumulation on the tooth surface. The clinical diagnosis of periodontal disease is based both on clinical examination involving the evaluation of probing depth and radiographic examination of alveolar bone loss but these examinations are not enough to determine the activity of the disease process. For that reason, it has been proposed to seek predictive disease markers in an attempt to assess the disease activity and so, evaluate the efficacy of the periodontal disease treatment. The aim of this review is to present recent advances in the development of proteomic, genomics and microbial biomarkers and potential clinical applications. It was concluded that periodontal treatment based on assessing the levels of salivary biomarkers emerges as a promising method in near future and will become an integral part of the evaluation of periodontal health.en
dc.description.affiliationUniversidade de Ponta Grossa, Departamento de Odontologia
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Diagnóstico e Cirurgia, Faculdade de Odontologia de Araraquara
dc.format.extent250-255
dc.identifierhttp://www.jaypeejournals.com/eJournals/Abstract.aspx?id=5422&AID=15&num=7
dc.identifier.citationWorld Journal of Dentistry, v. 4, n. 4, p. 250-255, 2013.
dc.identifier.doi10.5005/jp-journals-10015-1240
dc.identifier.issn0976-6006
dc.identifier.lattes9531839078426485
dc.identifier.urihttp://hdl.handle.net/11449/125627
dc.language.isoeng
dc.relation.ispartofWorld Journal of Dentistry
dc.relation.ispartofsjr0,107
dc.rights.accessRightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectSalivary glandsen
dc.subjectPeriodontal diseaseen
dc.subjectOral diagnosisen
dc.subjectPeriodontitisen
dc.titleUse of salivary biomarkers for diagnosis of periodontal disease activity: a literature reviewen
dc.typeArtigo
unesp.author.lattes9531839078426485
unesp.author.orcid0000-0003-1110-6233[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt
unesp.departmentDiagnóstico e Cirurgiapt

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Artigos - Diagnóstico e Cirurgia - FOAR