Chemical Composition and Antioxidant and Antimycobacterial Activities of Bromelia balansae (Bromeliaceae)

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dc.contributor.authorCoelho, Roberta Gomes
dc.contributor.authorHonda, Neli Kika
dc.contributor.authorVieira, Maria do Carmo
dc.contributor.authorBrum, Rosenei Louzada
dc.contributor.authorPavan, Fernando Rogério [UNESP]
dc.contributor.authorLeite, Clarice Queico Fujimura [UNESP]
dc.contributor.authorLima Cardoso, Claudia Andrea
dc.contributor.institutionUniversidade Federal de Mato Grosso do Sul (UFMS)
dc.contributor.institutionUniversidade Federal da Grande Dourados (UFGD)
dc.contributor.institutionUniv Estadual Mato Grosso do Sul
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:24:10Z
dc.date.available2014-05-20T13:24:10Z
dc.date.issued2010-10-01
dc.description.abstractBromelia balansae (Family Bromeliaceae) is a medicinal plant commonly used in the central region of Brazil as a cough syrup and also eaten roasted. The methanolic extract of ripe fruits was analyzed by chromatographic methods and spectrometrically. Four glycoside flavonols were isolated: kaempferol-3-O-alpha-l-rhamnopyranoside (1), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-d-glucopyranoside (2), quercetin-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside (3), and kaempferol 3,7-di-O-alpha-L-rhamnopyranoside (4). The resazurin microtiter assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis. The results showed a moderate activity of the methanolic extract with a minimal inhibitory concentration of 128 mu g/mL. Antioxidant activity was evaluated as free radical scavenging capacity and inhibition of peroxidation. Free radical scavenging capacity was assessed by measuring the scavenging activity of methanolic extract and methanolic fraction on 2,2-diphenyl-1-picrylhydrazyl radical. The methanolic extract showed low values of antioxidant activities, whereas the methanolic fraction exhibited free radical scavenging activity ranging from 20.2% to 91.1%, and the inhibition of peroxidation values ranging from 5.6% to 27.5%. This is the first chemical study reported in the literature about this species.en
dc.description.affiliationUniv Fed Mato Grosso do Sul, Dept Chem, BR-79070900 Campo Grande, MS, Brazil
dc.description.affiliationFed Univ Grande Dourados, Dept Agr, Dourados, MS, Brazil
dc.description.affiliationUniv Estadual Mato Grosso do Sul, Course Chem, Dourados, MS, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Pharmaceut Sci, Dept Biol Sci, São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Pharmaceut Sci, Dept Biol Sci, São Paulo, Brazil
dc.description.sponsorshipFundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul (FUNDECT)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 08/10390-2
dc.description.sponsorshipIdFAPESP: 09/06499-1
dc.format.extent1277-1280
dc.identifierhttp://dx.doi.org/10.1089/jmf.2009.0032
dc.identifier.citationJournal of Medicinal Food. New Rochelle: Mary Ann Liebert Inc., v. 13, n. 5, p. 1277-1280, 2010.
dc.identifier.doi10.1089/jmf.2009.0032
dc.identifier.fileWOS000282365600035.pdf
dc.identifier.issn1096-620X
dc.identifier.lattes2114570774349859
dc.identifier.urihttp://hdl.handle.net/11449/7417
dc.identifier.wosWOS:000282365600035
dc.language.isoeng
dc.publisherMary Ann Liebert, Inc.
dc.relation.ispartofJournal of Medicinal Food
dc.relation.ispartofjcr1.954
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectantioxidant activityen
dc.subjectantituberculosis activityen
dc.subjectBromelia balansaeen
dc.subjectBromeliaceaeen
dc.subjectcaraguata''en
dc.subjectflavonolsen
dc.subjectgravata''en
dc.subjectMycobacterium tuberculosisen
dc.titleChemical Composition and Antioxidant and Antimycobacterial Activities of Bromelia balansae (Bromeliaceae)en
dc.typeArtigo
dcterms.licensehttp://www.liebertpub.com/reprints/journal-of-medicinal-food/38/
dcterms.rightsHolderMary Ann Liebert Inc.
unesp.author.lattes2114570774349859
unesp.author.orcid0000-0002-6969-3963[5]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

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Artigos - Ciências Biológicas - FCFAR